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10.1016/j.ajem.2020.05.066 http://scihub22266oqcxt.onion/10.1016/j.ajem.2020.05.066 32475761!7251409!32475761     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Emerg+Med 2020 ; 38 (10): 2247.e1-2247.e2 Nephropedia Template TP {{tp|p=32475761|t=2020. Dexmedetomidine and worsening hypoxemia in the setting of COVID-19: A case report |pdf=|usr=}}{{32475761}} gab.com Text Dexmedetomidine and worsening hypoxemia in the setting of COVID-19: A case report JO: Am J Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=32475761 #FOAvip Emergency department management of hypoxemia in the setting of COVID-19 is riddled with uncertainty. The lack of high-quality research has translated to an absence of clarity at the bedside. With disease spread outpacing treatment consensus, provider discretion has taken on a heightened role. Here, we report a case of dexmedetomidine use in the setting of worsening hypoxemia, whereby oxygenation improved and intubation was avoided. Well known pharmacologic properties of the drug, namely the lack of respiratory depression and its anti-delirium effects, as well as other possible physiologic effects, suggest potential benefit for patients being managed with a delayed intubation approach. If dexmedetomidine can improve compliance with non-invasive oxygen support (the current recommended first-line therapy) while promoting better oxygenation, it may also decrease the need for mechanical ventilation and thus improve mortality. Twit Text FOAVip Dexmedetomidine and worsening hypoxemia in the setting of COVID-19: A case report ????Am J Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=32475761 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32475761 #FOAvip English Wikipedia <ref>{{Cite pmid|32475761}}</ref> Dexmedetomidine and worsening hypoxemia in the setting of COVID-19: A case report #MMPMID32475761 Stockton J; Kyle-Sidell C Am J Emerg Med 2020[Oct]; 38 (10): 2247.e1-2247.e2 PMID32475761show ga Emergency department management of hypoxemia in the setting of COVID-19 is riddled with uncertainty. The lack of high-quality research has translated to an absence of clarity at the bedside. With disease spread outpacing treatment consensus, provider discretion has taken on a heightened role. Here, we report a case of dexmedetomidine use in the setting of worsening hypoxemia, whereby oxygenation improved and intubation was avoided. Well known pharmacologic properties of the drug, namely the lack of respiratory depression and its anti-delirium effects, as well as other possible physiologic effects, suggest potential benefit for patients being managed with a delayed intubation approach. If dexmedetomidine can improve compliance with non-invasive oxygen support (the current recommended first-line therapy) while promoting better oxygenation, it may also decrease the need for mechanical ventilation and thus improve mortality. |COVID-19/*complications[MESH] |Dexmedetomidine/*administration & dosage/pharmacokinetics[MESH] |Female[MESH] |Humans[MESH] |Hypnotics and Sedatives/*administration & dosage/pharmacology[MESH] |Hypoxia/*drug therapy/etiology[MESH] |Middle Aged[MESH] |Oxygen Inhalation Therapy/methods[MESH]Dexmedetomidine and worsening hypoxemia in the setting of COVID-19: A (epmc).pdf DeepDyve Pubget Overpricing