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10.1007/s00330-020-06967-7

http://scihub22266oqcxt.onion/10.1007/s00330-020-06967-7
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32474630!7260475!32474630
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suck abstract from ncbi


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pmid32474630      Eur+Radiol 2020 ; 30 (11): 6161-6169
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  • Radiographic findings in 240 patients with COVID-19 pneumonia: time-dependence after the onset of symptoms #MMPMID32474630
  • Vancheri SG; Savietto G; Ballati F; Maggi A; Canino C; Bortolotto C; Valentini A; Dore R; Stella GM; Corsico AG; Iotti GA; Mojoli F; Perlini S; Bruno R; Preda L
  • Eur Radiol 2020[Nov]; 30 (11): 6161-6169 PMID32474630show ga
  • OBJECTIVE: To analyze the most frequent radiographic features of COVID-19 pneumonia and assess the effectiveness of chest X-ray (CXR) in detecting pulmonary alterations. MATERIALS AND METHODS: CXR of 240 symptomatic patients (70% male, mean age 65 +/- 16 years), with SARS-CoV-2 infection confirmed by RT-PCR, was retrospectively evaluated. Patients were clustered in four groups based on the number of days between symptom onset and CXR: group A (0-2 days), 49 patients; group B (3-5), 75 patients; group C (6-9), 85 patients; and group D (> 9), 31 patients. Alteration's type (reticular/ground-glass opacity (GGO)/consolidation) and distribution (bilateral/unilateral, upper/middle/lower fields, peripheral/central) were noted. Statistical significance was tested using chi-square test. RESULTS: Among 240 patients who underwent CXR, 180 (75%) showed alterations (group A, 63.3%; group B, 72%; group C, 81.2%; group D, 83.9%). GGO was observed in 124/180 patients (68.8%), reticular alteration in 113/180 (62.7%), and consolidation in 71/180 (39.4%). Consolidation was significantly less frequent (p < 0.01). Distribution among groups was as follows: reticular alteration (group A, 70.9%; group B, 72.2%; group C, 57.9%; group D, 46.1%), GGO (group A, 67.7%; group B, 62.9%; group C, 71%; group D, 76.9%), and consolidation (group A, 35.5%; group B, 31.4%; group C, 47.8%; group D, 38.5%). Alterations were bilateral in 73.3%. Upper, middle, and lower fields were involved in 36.7%, 79.4%, and 87.8%, respectively. Lesions were peripheral in 49.4%, central in 11.1%, or both in 39.4%. Upper fields and central zones were significantly less involved (p < 0.01). CONCLUSIONS: The most frequent lesions in COVID-19 patients were GGO (intermediate/late phase) and reticular alteration (early phase) while consolidation gradually increased over time. The most frequent distribution was bilateral, peripheral, and with middle/lower predominance. Overall rate of negative CXR was 25%, which progressively decreased over time. KEY POINTS: * The predominant lung changes were GGO and reticular alteration, while consolidation was less frequent. * The typical distribution pattern was bilateral, peripheral, or both peripheral and central and involved predominantly the lower and middle fields. * Chest radiography showed lung abnormalities in 75% of patients with confirmed SARS-CoV-2 infection, range varied from 63.3 to 83.9%, respectively, at 0-2 days and > 9 days from the onset of symptoms.
  • |*Betacoronavirus[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19[MESH]
  • |Chi-Square Distribution[MESH]
  • |Coronavirus Infections/*diagnostic imaging/*pathology/physiopathology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lung/diagnostic imaging/pathology/physiopathology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnostic imaging/*pathology/physiopathology[MESH]
  • |Radiography, Thoracic/*methods[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]
  • |Time Factors[MESH]


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