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Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Nat+Commun 2020 ; 11 (1): 2800 Nephropedia Template TP
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Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients #MMPMID32472043
Chia PY; Coleman KK; Tan YK; Ong SWX; Gum M; Lau SK; Lim XF; Lim AS; Sutjipto S; Lee PH; Son TT; Young BE; Milton DK; Gray GC; Schuster S; Barkham T; De PP; Vasoo S; Chan M; Ang BSP; Tan BH; Leo YS; Ng OT; Wong MSY; Marimuthu K
Nat Commun 2020[May]; 11 (1): 2800 PMID32472043show ga
Understanding the particle size distribution in the air and patterns of environmental contamination of SARS-CoV-2 is essential for infection prevention policies. Here we screen surface and air samples from hospital rooms of COVID-19 patients for SARS-CoV-2 RNA. Environmental sampling is conducted in three airborne infection isolation rooms (AIIRs) in the ICU and 27 AIIRs in the general ward. 245 surface samples are collected. 56.7% of rooms have at least one environmental surface contaminated. High touch surface contamination is shown in ten (66.7%) out of 15 patients in the first week of illness, and three (20%) beyond the first week of illness (p = 0.01, chi(2) test). Air sampling is performed in three of the 27 AIIRs in the general ward, and detects SARS-CoV-2 PCR-positive particles of sizes >4 microm and 1-4 microm in two rooms, despite these rooms having 12 air changes per hour. This warrants further study of the airborne transmission potential of SARS-CoV-2.