Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText.
Kick-your-searchterm to multiple Engines kick-your-query now !>
A dictionary by aggregated review articles of nephrology, medicine and the life sciences
Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

suck abstract from ncbi


10.18632/aging.103344

http://scihub22266oqcxt.onion/10.18632/aging.103344
suck pdf from google scholar
32470948!7288963!32470948
unlimited free pdf from europmc32470948    free
PDF from PMC    free
html from PMC    free

suck abstract from ncbi


Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
pmid32470948      Aging+(Albany+NY) 2020 ; 12 (10): 9959-9981
Nephropedia Template TP

gab.com Text

Twit Text FOAVip

Twit Text #

English Wikipedia


  • Why does COVID-19 disproportionately affect older people? #MMPMID32470948
  • Mueller AL; McNamara MS; Sinclair DA
  • Aging (Albany NY) 2020[May]; 12 (10): 9959-9981 PMID32470948show ga
  • The severity and outcome of coronavirus disease 2019 (COVID-19) largely depends on a patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23-fold greater risk of death than those under 65. In the clinic, COVID-19 patients most commonly present with fever, cough and dyspnea, and from there the disease can progress to acute respiratory distress syndrome, lung consolidation, cytokine release syndrome, endotheliitis, coagulopathy, multiple organ failure and death. Comorbidities such as cardiovascular disease, diabetes and obesity increase the chances of fatal disease, but they alone do not explain why age is an independent risk factor. Here, we present the molecular differences between young, middle-aged and older people that may explain why COVID-19 is a mild illness in some but life-threatening in others. We also discuss several biological age clocks that could be used in conjunction with genetic tests to identify both the mechanisms of the disease and individuals most at risk. Finally, based on these mechanisms, we discuss treatments that could increase the survival of older people, not simply by inhibiting the virus, but by restoring patients' ability to clear the infection and effectively regulate immune responses.
  • |*Coronavirus Infections/epidemiology/immunology/therapy[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral/epidemiology/immunology/therapy[MESH]
  • |Aged[MESH]
  • |Aging/*physiology[MESH]
  • |Betacoronavirus/isolation & purification/physiology[MESH]
  • |COVID-19[MESH]
  • |Comorbidity[MESH]
  • |Cytokine Release Syndrome/etiology/immunology[MESH]
  • |Epigenesis, Genetic/*physiology[MESH]
  • |Humans[MESH]
  • |Immunity/*physiology[MESH]
  • |Patient Care Management/*methods[MESH]
  • |Respiratory Distress Syndrome/etiology/immunology[MESH]
  • |Risk Assessment[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]


  • DeepDyve
  • Pubget Overpricing
  • suck abstract from ncbi

    Linkout box