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10.3201/eid2608.201423

http://scihub22266oqcxt.onion/10.3201/eid2608.201423
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32470316!7392438!32470316
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suck abstract from ncbi


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pmid32470316      Emerg+Infect+Dis 2020 ; 26 (8): 1671-1678
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  • Investigation and Serologic Follow-Up of Contacts of an Early Confirmed Case-Patient with COVID-19, Washington, USA #MMPMID32470316
  • Chu VT; Freeman-Ponder B; Lindquist S; Spitters C; Kawakami V; Dyal JW; Clark S; Bruce H; Duchin JS; DeBolt C; Podczervinski S; D'Angeli M; Pettrone K; Zacks R; Vahey G; Holshue ML; Lang M; Burke RM; Rolfes MA; Marlow M; Midgley CM; Lu X; Lindstrom S; Hall AJ; Fry AM; Thornburg NJ; Gerber SI; Pillai SK; Biggs HM
  • Emerg Infect Dis 2020[Aug]; 26 (8): 1671-1678 PMID32470316show ga
  • We describe the contact investigation for an early confirmed case of coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in the United States. Contacts of the case-patient were identified, actively monitored for symptoms, interviewed for a detailed exposure history, and tested for SARS-CoV-2 infection by real-time reverse transcription PCR (rRT-PCR) and ELISA. Fifty contacts were identified and 38 (76%) were interviewed, of whom 11 (29%) reported unprotected face-to-face interaction with the case-patient. Thirty-seven (74%) had respiratory specimens tested by rRT-PCR, and all tested negative. Twenty-three (46%) had ELISA performed on serum samples collected approximately 6 weeks after exposure, and none had detectable antibodies to SARS-CoV-2. Among contacts who were tested, no secondary transmission was identified in this investigation, despite unprotected close interactions with the infectious case-patient.
  • |*Pandemics[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Betacoronavirus/genetics/*pathogenicity[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Clinical Laboratory Techniques/methods[MESH]
  • |Contact Tracing/*statistics & numerical data[MESH]
  • |Coronavirus Infections/diagnosis/*epidemiology[MESH]
  • |Enzyme-Linked Immunosorbent Assay[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Infant, Newborn[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pneumonia, Viral/diagnosis/*epidemiology[MESH]
  • |Public Health/methods[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]
  • |Travel[MESH]


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