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10.1002/jmv.26082

http://scihub22266oqcxt.onion/10.1002/jmv.26082
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suck abstract from ncbi


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pmid32470186      J+Med+Virol 2020 ; 92 (11): 2616-2622
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  • Correlation between the variables collected at admission and progression to severe cases during hospitalization among patients with COVID-19 in Chongqing #MMPMID32470186
  • Duan J; Wang X; Chi J; Chen H; Bai L; Hu Q; Han X; Hu W; Zhu L; Wang X; Li Y; Zhou C; Mou H; Yan X; Guo S
  • J Med Virol 2020[Nov]; 92 (11): 2616-2622 PMID32470186show ga
  • Mortality is high among severe patients with 2019 novel coronavirus-infected disease (COVID-19). Early prediction of progression to severe cases is needed. We retrospectively collected patients with COVID-19 in two hospital of Chongqing from 1st January to 29th February 2020. At admission, we collected the demographics and laboratory tests to predict whether the patient would progress to severe cases in hospitalization. Severe case was confirmed when one of the following criteria occurred: (a) dyspnea, respiratory rate >/=30 breaths/min, (b) blood oxygen saturation /= 0.8). Age, heart rate, chlorine, alanine aminotransferase, aspartate aminotransferase, procalcitonin, creatine kinase, pH, CD3 counts, and CD4 counts showed moderate distinguishing power (each AUC between 0.7-0.8). And potassium, creatinine, temperature, and D-dimer showed mild distinguishing power (each AUC between 0.6-0.7). In addition, higher C-reactive protein was associated with shorter time to progress to severe cases (r = -0.62). Several easily obtained variables at admission are associated with progression to severe cases during hospitalization. These variables provide a reference for the medical staffs when they manage the patients with COVID-19.
  • |*Severity of Illness Index[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |C-Reactive Protein/analysis[MESH]
  • |COVID-19/*diagnosis/mortality[MESH]
  • |China/epidemiology[MESH]
  • |Comorbidity[MESH]
  • |Disease Progression[MESH]
  • |Female[MESH]
  • |Hospitalization/*statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Platelet Count/statistics & numerical data[MESH]
  • |ROC Curve[MESH]
  • |Retrospective Studies[MESH]


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