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10.1371/journal.pone.0233605 http://scihub22266oqcxt.onion/10.1371/journal.pone.0233605 32470010!7259782!32470010     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32470010&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       PLoS+One 2020 ; 15 (5): e0233605 Nephropedia Template TP {{tp|p=32470010|t=2020. Harnessing the potential of blood donation archives for influenza surveillance and control |pdf=|usr=}}{{32470010}} gab.com Text Harnessing the potential of blood donation archives for influenza surveillance and control JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=32470010 #FOAvip Many blood donation services around the globe maintain large archives of serum and/or plasma specimens of blood donations which could potentially be used for serologic surveillance and risk assessment of influenza. Harnessing this potential requires robust evidence that the outcomes of influenza serology in plasma, which is rarely used, is consistent with that in serum, which is the conventional choice of specimens for influenza serology. We harvested EDTA-plasma specimens from the blood donation archives of Hong Kong Red Cross Transfusion Services, where EDTA is the type of anticoagulant used for plasma collection, compared their antibody titers and responses to that in serum. Influenza A/H1N1/California/7/2009 and A/H3N2/Victoria/208/2009 were the test strains. Our results showed that antibody titers in 609 matched serum/EDTA-plasma specimens (i.e. obtained from the same donor at the same time) had good agreement inferred by Intraclass Correlation Coefficient, the value of which was 0.82 (95% CI: 0.77-0.86) for hemagglutination inhibition assay and 0.95 (95% CI: 0.93-0.96) for microneutralization assay; seroconversion rates (based on hemagglutination inhibition titers) during the 2010 and 2011 influenza seasons in Hong Kong inferred from paired EDTA-plasma were similar to that inferred from paired sera. Our study provided the proof-of-concept that blood donation archives could be leveraged as a valuable source of longitudinal blood specimens for the surveillance, control and risk assessment of both pandemic and seasonal influenza. Twit Text FOAVip Harnessing the potential of blood donation archives for influenza surveillance and control ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=32470010 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32470010 #FOAvip English Wikipedia <ref>{{Cite pmid|32470010}}</ref> Harnessing the potential of blood donation archives for influenza surveillance and control #MMPMID32470010 Zhang Y; Leung K; Perera RAPM; Lee CK; Peiris JSM; Wu JT PLoS One 2020[]; 15 (5): e0233605 PMID32470010show ga Many blood donation services around the globe maintain large archives of serum and/or plasma specimens of blood donations which could potentially be used for serologic surveillance and risk assessment of influenza. Harnessing this potential requires robust evidence that the outcomes of influenza serology in plasma, which is rarely used, is consistent with that in serum, which is the conventional choice of specimens for influenza serology. We harvested EDTA-plasma specimens from the blood donation archives of Hong Kong Red Cross Transfusion Services, where EDTA is the type of anticoagulant used for plasma collection, compared their antibody titers and responses to that in serum. Influenza A/H1N1/California/7/2009 and A/H3N2/Victoria/208/2009 were the test strains. Our results showed that antibody titers in 609 matched serum/EDTA-plasma specimens (i.e. obtained from the same donor at the same time) had good agreement inferred by Intraclass Correlation Coefficient, the value of which was 0.82 (95% CI: 0.77-0.86) for hemagglutination inhibition assay and 0.95 (95% CI: 0.93-0.96) for microneutralization assay; seroconversion rates (based on hemagglutination inhibition titers) during the 2010 and 2011 influenza seasons in Hong Kong inferred from paired EDTA-plasma were similar to that inferred from paired sera. Our study provided the proof-of-concept that blood donation archives could be leveraged as a valuable source of longitudinal blood specimens for the surveillance, control and risk assessment of both pandemic and seasonal influenza. |*Blood Banks[MESH] |*Blood Donors[MESH] |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Antibodies, Viral/blood/immunology[MESH] |Cross-Sectional Studies[MESH] |Epidemiological Monitoring[MESH] |Hong Kong/epidemiology[MESH] |Humans[MESH] |Influenza A Virus, H1N1 Subtype/immunology/isolation & purification[MESH] |Influenza A Virus, H3N2 Subtype/immunology/isolation & purification[MESH] |Influenza, Human/*blood/*epidemiology/immunology[MESH] |Middle Aged[MESH]Harnessing the potential of blood donation archives for influenza surv(epmc).pdf DeepDyve Pubget Overpricing