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10.1177/0145561320929169

http://scihub22266oqcxt.onion/10.1177/0145561320929169
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32469246!ä!32469246

suck abstract from ncbi


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pmid32469246      Ear+Nose+Throat+J 2020 ; 99 (9): 579-583
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  • Psychophysical Olfactory Tests and Detection of COVID-19 in Patients With Sudden Onset Olfactory Dysfunction: A Prospective Study #MMPMID32469246
  • Lechien JR; Cabaraux P; Chiesa-Estomba CM; Khalife M; Plzak J; Hans S; Martiny D; Calvo-Henriquez C; Barillari MR; Hopkins C; Saussez S
  • Ear Nose Throat J 2020[Nov]; 99 (9): 579-583 PMID32469246show ga
  • OBJECTIVE: To investigate the coronavirus disease 2019 (COVID-19) status of patients with initial sudden olfactory anosmia (ISOA) through nasopharyngeal swabs for reverse transcription-polymerase chain reaction (RT-PCR) analysis and to explore their olfactory dysfunctions with psychophysical olfactory evaluation. METHODS: A total of 78 ISOA patients were recruited from April 6, 2020, to April 10, 2020, through a public call of University of Mons (Mons, Belgium). Patients benefited from nasopharyngeal swabs and fulfilled the patient-reported outcome questionnaire. Among them, 46 patients performed psychophysical olfactory evaluation using olfactory identification testing. Based on the duration of the ISOA, 2 groups of patients were compared: patients with olfactory dysfunction duration 12 days (group 2). RESULTS: In group 1, 42 patients (87.5%) had a positive viral load determined by RT-PCR and 6 patients (12.5%) were negative. In group 2, 7 patients (23%) had a positive viral load and 23 patients (77%) were negative. The psychophysical olfactory evaluation reported that anosmia and hyposmia occurred in 24 (52%) and 11 (24%) patients, respectively. Eleven patients were normosmic. The viral load was significantly higher in patients of group 1 compared with those of group 2. CONCLUSIONS: Coronavirus disease 2019 was detected in a high proportion of ISOA patients, especially over the first 12 days of olfactory dysfunction. Anosmia is an important symptom to consider in the detection of COVID-19 infection.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Belgium[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Case-Control Studies[MESH]
  • |Clinical Laboratory Techniques[MESH]
  • |Coronavirus Infections/complications/*diagnosis[MESH]
  • |Diagnostic Techniques, Respiratory System[MESH]
  • |Dysgeusia[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nasal Obstruction[MESH]
  • |Odorants[MESH]
  • |Olfaction Disorders/complications/*diagnosis[MESH]
  • |Pandemics[MESH]
  • |Patient Reported Outcome Measures[MESH]
  • |Physical Stimulation[MESH]
  • |Pneumonia, Viral/complications/*diagnosis[MESH]
  • |Prospective Studies[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]


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