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10.1161/STROKEAHA.120.030365

http://scihub22266oqcxt.onion/10.1161/STROKEAHA.120.030365
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suck abstract from ncbi


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pmid32466735      Stroke 2020 ; 51 (7): 2219-2223
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  • Clinical Characteristics and Outcomes of COVID-19 Patients With a History of Stroke in Wuhan, China #MMPMID32466735
  • Qin C; Zhou L; Hu Z; Yang S; Zhang S; Chen M; Yu H; Tian DS; Wang W
  • Stroke 2020[Jul]; 51 (7): 2219-2223 PMID32466735show ga
  • BACKGROUND AND PURPOSE: Information on stroke survivors infected with coronavirus disease 2019 (COVID-19) is limited. The aim of this study was to describe specific clinical characteristics and outcomes of patients with COVID-19 with a history of stroke. METHODS: All the confirmed cases of COVID-19 at Tongji Hospital from January 27 to March 5, 2020, were included in our cohort study. Clinical data were analyzed and compared between patients with and without a history of stroke. RESULTS: Of the included 1875 patients with COVID-19, 50 patients had a history of stroke. The COVID-19 patients with medical history of stroke were older with more comorbidities, had higher neutrophil count, and lower lymphocyte and platelet counts than those without history of stroke. The levels of D-dimers, cardiac troponin I, NT pro-brain natriuretic peptide, and interleukin-6 were also markedly higher in patients with history of stroke. Stroke survivors who underwent COVID-19 developed more acute respiratory distress syndrome and received more noninvasive mechanical ventilation. Data from propensity-matched analysis indicated a higher proportion of patients with COVD-19 with a history of stroke were admitted to the intensive care unit requiring mechanical ventilation and were more likely to be held in the unit or die, compared with non-stroke history COVID-19 patients. CONCLUSIONS: Patients with COVID-19 with a history of stroke had more severe clinical symptoms and poorer outcomes compared with those without a history of stroke.
  • |*Betacoronavirus[MESH]
  • |*Coronavirus Infections/epidemiology[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral/epidemiology[MESH]
  • |Aged[MESH]
  • |Blood Cell Count[MESH]
  • |COVID-19[MESH]
  • |China/epidemiology[MESH]
  • |Comorbidity[MESH]
  • |Female[MESH]
  • |Hospital Mortality[MESH]
  • |Hospitals, University/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Procedures and Techniques Utilization[MESH]
  • |Propensity Score[MESH]
  • |Recurrence[MESH]
  • |Respiration, Artificial/statistics & numerical data[MESH]
  • |Respiratory Distress Syndrome/etiology/therapy[MESH]
  • |SARS-CoV-2[MESH]
  • |Stroke/blood/*epidemiology/therapy[MESH]


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