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10.1016/j.chom.2020.05.008 http://scihub22266oqcxt.onion/10.1016/j.chom.2020.05.008 32464097!7255347!32464097     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Host+Microbe 2020 ; 27 (6): 870-878 Nephropedia Template TP {{tp|p=32464097|t=2020. Type I and Type III Interferons - Induction, Signaling, Evasion, and Application to Combat COVID-19 |pdf=|usr=}}{{32464097}} gab.com Text Type I and Type III Interferons - Induction, Signaling, Evasion, and Application to Combat COVID-19 JO: Cell Host Microbe http://www.kidney.de/pget.php?&tw=1&pmid=32464097 #FOAvip Coronavirus disease 2019 (COVID-19) is a global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Without approved antiviral therapeutics or vaccines to this ongoing global threat, type I and type III interferons (IFNs) are currently being evaluated for their efficacy. Both the role of IFNs and the use of recombinant IFNs in two related, highly pathogenic coronaviruses, SARS-CoV and MERS-CoV, have been controversial in terms of their protective effects in the host. In this review, we describe the recent progress in our understanding of both type I and type III IFN-mediated innate antiviral responses against human coronaviruses and discuss the potential use of IFNs as a treatment strategy for COVID-19. Twit Text FOAVip Type I and Type III Interferons - Induction, Signaling, Evasion, and Application to Combat COVID-19 ????Cell Host Microbe http://www.kidney.de/pget.php?&tw=1&pmid=32464097 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32464097 #FOAvip English Wikipedia <ref>{{Cite pmid|32464097}}</ref> Type I and Type III Interferons - Induction, Signaling, Evasion, and Application to Combat COVID-19 #MMPMID32464097 Park A; Iwasaki A Cell Host Microbe 2020[Jun]; 27 (6): 870-878 PMID32464097show ga Coronavirus disease 2019 (COVID-19) is a global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Without approved antiviral therapeutics or vaccines to this ongoing global threat, type I and type III interferons (IFNs) are currently being evaluated for their efficacy. Both the role of IFNs and the use of recombinant IFNs in two related, highly pathogenic coronaviruses, SARS-CoV and MERS-CoV, have been controversial in terms of their protective effects in the host. In this review, we describe the recent progress in our understanding of both type I and type III IFN-mediated innate antiviral responses against human coronaviruses and discuss the potential use of IFNs as a treatment strategy for COVID-19. |Animals[MESH] |Antiviral Agents/pharmacology[MESH] |Betacoronavirus/*physiology[MESH] |COVID-19[MESH] |Coronavirus Infections/drug therapy/*immunology/pathology/virology[MESH] |Humans[MESH] |Immune Evasion[MESH] |Interferon Lambda[MESH] |Interferon Type I/genetics/*immunology/pharmacology[MESH] |Interferons/genetics/*immunology/pharmacology[MESH] |Pandemics[MESH] |Pneumonia, Viral/drug therapy/*immunology/pathology/virology[MESH] |Recombinant Proteins/pharmacology[MESH] |SARS-CoV-2[MESH]Type I and Type III Interferons - Induction, Signaling, Evasion, and A(epmc).pdf DeepDyve Pubget Overpricing