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10.1002/jmv.26075

http://scihub22266oqcxt.onion/10.1002/jmv.26075
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suck abstract from ncbi


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pmid32462705      J+Med+Virol 2020 ; 92 (10): 2209-2215
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  • Clinical features, isolation, and complete genome sequence of severe acute respiratory syndrome coronavirus 2 from the first two patients in Vietnam #MMPMID32462705
  • Phan LT; Nguyen TV; Huynh LKT; Dao MH; Vo TAN; Vu NHP; Pham HTT; Nguyen HT; Nguyen TT; Le HQ; Nguyen TV; Nguyen QH; Huynh TP; Nguyen SN; Nguyen AH; Nguyen NT; Nguyen TNT; Nguyen LT; Luong QC; Cao TM; Pham QD
  • J Med Virol 2020[Oct]; 92 (10): 2209-2215 PMID32462705show ga
  • In January 2020, we identified two severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients in a familial cluster with one person coming from Wuhan, China. The complete genome sequences of two SARS-CoV-2 strains isolated from these patients were identical and 99.98% similar to strains isolated in Wuhan. This is genetically suggestive of human-to-human transmission of SARS-CoV-2 and indicates Wuhan as the most plausible origin of the early outbreak in Vietnam. The younger patient had a mild upper respiratory illness and a brief viral shedding, whereas the elderly with multi-morbidity had pneumonia, prolonged viral shedding, and residual lung damage. The evidence of nonsynonymous substitutions in the ORF1ab region of the viral sequence warrants further studies.
  • |*Genome, Viral[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/diagnosis/pathology/*transmission/virology[MESH]
  • |China/epidemiology[MESH]
  • |Family[MESH]
  • |Genotype[MESH]
  • |Humans[MESH]
  • |Lung/pathology/*virology[MESH]
  • |Male[MESH]
  • |Mutation[MESH]
  • |Phylogeny[MESH]
  • |SARS-CoV-2/classification/*genetics/isolation & purification/pathogenicity[MESH]
  • |Travel[MESH]
  • |Vietnam/epidemiology[MESH]
  • |Virus Replication[MESH]


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  • suck abstract from ncbi

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