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10.1111/imm.13223 http://scihub22266oqcxt.onion/10.1111/imm.13223 32460357!7283723!32460357     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunology 2020 ; 160 (3): 261-268 Nephropedia Template TP {{tp|p=32460357|t=2020. Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou, China |pdf=|usr=}}{{32460357}} gab.com Text Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou, China JO: Immunology http://www.kidney.de/pget.php?&tw=1&pmid=32460357 #FOAvip Coronavirus disease 2019 (COVID-19) is a respiratory disorder caused by the highly contagious severe acute respiratory syndrome coronavirus 2. The immunopathological characteristics of patients with COVID-19, either systemic or local, have not been thoroughly studied. In the present study, we analysed both the changes in the number of various immune cell types as well as cytokines important for immune reactions and inflammation. Our data indicate that patients with severe COVID-19 exhibited an overall decline of lymphocytes including CD4(+) and CD8(+) T cells, B cells and natural killer cells. The number of immunosuppressive regulatory T cells was moderately increased in patients with mild COVID-19. Interleukin-6 (IL-6), IL-10 and C-reactive protein were remarkably up-regulated in patients with severe COVID-19. In conclusion, our study shows that the comprehensive decrease of lymphocytes, and the elevation of IL-6, IL-10 and C-reactive protein are reliable indicators of severe COVID-19. Twit Text FOAVip Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou, China ????Immunology http://www.kidney.de/pget.php?&tw=1&pmid=32460357 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32460357 #FOAvip English Wikipedia <ref>{{Cite pmid|32460357}}</ref> Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou, China #MMPMID32460357 Tan M; Liu Y; Zhou R; Deng X; Li F; Liang K; Shi Y Immunology 2020[Jul]; 160 (3): 261-268 PMID32460357show ga Coronavirus disease 2019 (COVID-19) is a respiratory disorder caused by the highly contagious severe acute respiratory syndrome coronavirus 2. The immunopathological characteristics of patients with COVID-19, either systemic or local, have not been thoroughly studied. In the present study, we analysed both the changes in the number of various immune cell types as well as cytokines important for immune reactions and inflammation. Our data indicate that patients with severe COVID-19 exhibited an overall decline of lymphocytes including CD4(+) and CD8(+) T cells, B cells and natural killer cells. The number of immunosuppressive regulatory T cells was moderately increased in patients with mild COVID-19. Interleukin-6 (IL-6), IL-10 and C-reactive protein were remarkably up-regulated in patients with severe COVID-19. In conclusion, our study shows that the comprehensive decrease of lymphocytes, and the elevation of IL-6, IL-10 and C-reactive protein are reliable indicators of severe COVID-19. |Aged[MESH] |B-Lymphocytes/immunology/pathology[MESH] |Betacoronavirus/physiology[MESH] |COVID-19[MESH] |China/epidemiology[MESH] |Coronavirus Infections/epidemiology/*immunology/*pathology/physiopathology[MESH] |Female[MESH] |Humans[MESH] |Killer Cells, Natural/immunology/pathology[MESH] |Lymphocytes/pathology[MESH] |Male[MESH] |Pandemics[MESH] |Pneumonia, Viral/epidemiology/*immunology/*pathology/physiopathology[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH] |T-Lymphocytes, Regulatory/pathology[MESH]Immunopathological characteristics of coronavirus disease 2019 cases i(epmc).pdf DeepDyve Pubget Overpricing