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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Cytokine 2020 ; 133 (ä): 155143 Nephropedia Template TP
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Altered cytokine levels and immune responses in patients with SARS-CoV-2 infection and related conditions #MMPMID32460144
Noroozi R; Branicki W; Pyrc K; Labaj PP; Pospiech E; Taheri M; Ghafouri-Fard S
Cytokine 2020[Sep]; 133 (ä): 155143 PMID32460144show ga
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic in early 2020. The infection has been associated with a wide range of clinical symptoms. In the severely affected patients, it has caused dysregulation of immune responses including over-secretion of inflammatory cytokines and imbalances in the proportion of naive helper T cells, memory helper T cells and regulatory T cells. Identification of the underlying mechanism of such aberrant function of immune system would help in the prediction of disease course and selection of susceptible patients for more intensive cares. In the current review, we summarize the results of studies which reported alterations in cytokine levels and immune cell functions in patients affected with SARS-CoV-2 and related viruses.