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10.1002/jmv.26064

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suck abstract from ncbi


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pmid32458502      J+Med+Virol 2020 ; 92 (10): 2200-2204
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  • Glycyrrhetinic acid and its derivatives as potential alternative medicine to relieve symptoms in nonhospitalized COVID-19 patients #MMPMID32458502
  • Ding H; Deng W; Ding L; Ye X; Yin S; Huang W
  • J Med Virol 2020[Oct]; 92 (10): 2200-2204 PMID32458502show ga
  • SARS-CoV-2 is highly infectious, and infection by this virus results in COVID-19, manifesting predominantly symptoms in the lower respiratory system. Detection of viral genomic materials by RT-PCR is the gold standard for diagnosis. Suspected COVID-19 patients who had a documented history of exposure and exhibited symptoms, but did not have positive PCR test results, were generally self-quarantined with prescriptions aiming to help attenuate their symptoms. These prescriptions are however neither specific nor highly effective for COVID-19 treatment. Given the rapidly growing pandemic and the overwhelmed medical system, the number of self-quarantined patients is increasing. There is an urgent need of alternative medicine to help patients relieve symptoms during self-quarantine, and to potentially help increase their chances of survival and recovery from the infection. We report here a case of severe COVID-19 that never had a positive PCR test result during disease progression but was confirmed with antibody test post recovery. This patient was self-quarantined and received diammonium glycyrrhizinate (DG), a steroid-like molecule, in combination with vitamin C as alternative medicine. This patient went through severe COVID-19 but eventually recovered upon the implementation of this treatment regimen, suggesting potential therapeutic effects of DG as alternative medicine to help relieve COVID-19 symptoms.
  • |*COVID-19 Drug Treatment[MESH]
  • |Ascorbic Acid/therapeutic use[MESH]
  • |Complementary Therapies/methods[MESH]
  • |Female[MESH]
  • |Glycyrrhetinic Acid/*therapeutic use[MESH]
  • |Humans[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/drug therapy/virology[MESH]


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