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10.1080/09537104.2020.1768523

http://scihub22266oqcxt.onion/10.1080/09537104.2020.1768523
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32456506!ä!32456506

suck abstract from ncbi


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pmid32456506      Platelets 2020 ; 31 (6): 740-745
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  • Hemostatic laboratory derangements in COVID-19 with a focus on platelet count #MMPMID32456506
  • Amgalan A; Othman M
  • Platelets 2020[Aug]; 31 (6): 740-745 PMID32456506show ga
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease in 2019 (COVID-19) which rapidly evolved from an outbreak in Wuhan, China into a pandemic that has resulted in over millions of infections and over hundreds of thousands of mortalities worldwide. Various coagulopathies have been reported in association with COVID-19, including disseminated intravascular coagulation (DIC), sepsis-induced coagulopathy (SIC), local microthrombi, venous thromboembolism (VTE), arterial thrombotic complications, and thrombo-inflammation. There is a plethora of publications and conflicting data on hematological and hemostatic derangements in COVID-19 with some data suggesting the link to disease progress, severity and/or mortality. There is also growing evidence of potentially useful clinical biomarkers to predict COVID-19 progression and disease outcomes. Of those, a link between thrombocytopenia and COVID-19 severity or mortality was suggested. In this opinion report, we examine the published evidence of hematological and hemostatic laboratory derangements in COVID-19 and the interrelated SARS-CoV-2 induced inflammation, with a focussed discussion on platelet count alterations. We explore whether thrombocytopenia could be a potential disease biomarker and we provide recommendations for future studies in this regard.
  • |*Betacoronavirus[MESH]
  • |*Pandemics[MESH]
  • |*Platelet Count[MESH]
  • |Blood Cell Count[MESH]
  • |Blood Coagulation Disorders/blood/*etiology[MESH]
  • |Blood Coagulation Tests[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*blood/complications[MESH]
  • |Disseminated Intravascular Coagulation/blood/etiology[MESH]
  • |Humans[MESH]
  • |Inflammation/blood/etiology[MESH]
  • |Pneumonia, Viral/*blood/complications[MESH]
  • |SARS-CoV-2[MESH]
  • |Thrombelastography[MESH]
  • |Thrombocytopenia/blood/*etiology[MESH]
  • |Thrombocytosis/blood/*etiology[MESH]


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