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10.1556/650.2020.31870 http://scihub22266oqcxt.onion/10.1556/650.2020.31870 32453702!ä!32453702 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Orv+Hetil 2020 ; 161 (22): 899-907 Nephropedia Template TP {{tp|p=32453702|t=2020. Procoagulatio, hypercoagulatio es fibrinolysis "shut down" kimutatasa ClotPro(R) viszkoelasztikus tesztek segitsegevel COVID-19-betegekben |pdf=|usr=}}{{32453702}} gab.com Text Procoagulatio, hypercoagulatio es fibrinolysis "shut down" kimutatasa ClotPro(R) viszkoelasztikus tesztek segitsegevel COVID-19-betegekben JO: Orv Hetil http://www.kidney.de/pget.php?&tw=1&pmid=32453702 #FOAvip INTRODUCTION: International data indicate that arterial, venous and microvascular thrombosis or disseminated intravascular coagulation occur in more than 30% of hospitalized patients with COVID-19. This condition is characterized by high levels of D-dimer and fibrinogen, prolonged prothrombin time and activated partial thromboplastin time. METHOD: Blood samples from three COVID-19 patients treated in a Hungarian intensive care unit were collected and analyzed with ClotPro(R) tests. EX-tests, IN-test, FIB-tests, RVV-tests, and TPA-tests were performed. The results were interpreted with respect to the clinical condition of the patients. RESULTS: Procoagulation, hypercoagulation and either fibrinolysis or a "shut down" phenomenon of the fibrinolytic process were found with ClotPro(R). The ClotPro(R) parameters were consistent with the conventional coagulation tests and corresponded with the criteria of non-overt disseminated intravascular coagulation. CONCLUSION: These findings encourage further investigations to elucidate the underlying pathophysiology of thromboembolic events in COVID-19 patients and may support the introduction of full dose anticoagulation with or without antiplatelet therapy. Interventional clinical trials may be helpful in defining the appropriate drug(s), for this purpose, the algorithms of administration, and the optimal duration of therapy. At present, the authorization of a clinical trial that attempts to answer these questions is in progress. Orv Hetil. 2020; 161(22): 899-907. Twit Text FOAVip Procoagulatio, hypercoagulatio es fibrinolysis "shut down" kimutatasa ClotPro(R) viszkoelasztikus tesztek segitsegevel COVID-19-betegekben ????Orv Hetil http://www.kidney.de/pget.php?&tw=1&pmid=32453702 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32453702 #FOAvip English Wikipedia <ref>{{Cite pmid|32453702}}</ref> Procoagulatio, hypercoagulatio es fibrinolysis "shut down" kimutatasa ClotPro(R) viszkoelasztikus tesztek segitsegevel COVID-19-betegekben #MMPMID32453702 Zatroch I; Smudla A; Babik B; Tanczos K; Kobori L; Szabo Z; Fazakas J Orv Hetil 2020[May]; 161 (22): 899-907 PMID32453702show ga INTRODUCTION: International data indicate that arterial, venous and microvascular thrombosis or disseminated intravascular coagulation occur in more than 30% of hospitalized patients with COVID-19. This condition is characterized by high levels of D-dimer and fibrinogen, prolonged prothrombin time and activated partial thromboplastin time. METHOD: Blood samples from three COVID-19 patients treated in a Hungarian intensive care unit were collected and analyzed with ClotPro(R) tests. EX-tests, IN-test, FIB-tests, RVV-tests, and TPA-tests were performed. The results were interpreted with respect to the clinical condition of the patients. RESULTS: Procoagulation, hypercoagulation and either fibrinolysis or a "shut down" phenomenon of the fibrinolytic process were found with ClotPro(R). The ClotPro(R) parameters were consistent with the conventional coagulation tests and corresponded with the criteria of non-overt disseminated intravascular coagulation. CONCLUSION: These findings encourage further investigations to elucidate the underlying pathophysiology of thromboembolic events in COVID-19 patients and may support the introduction of full dose anticoagulation with or without antiplatelet therapy. Interventional clinical trials may be helpful in defining the appropriate drug(s), for this purpose, the algorithms of administration, and the optimal duration of therapy. At present, the authorization of a clinical trial that attempts to answer these questions is in progress. Orv Hetil. 2020; 161(22): 899-907. |Blood Coagulation Tests[MESH] |COVID-19[MESH] |Coronavirus Infections/*physiopathology/*therapy[MESH] |Disseminated Intravascular Coagulation/*diagnosis[MESH] |Humans[MESH] |Pandemics[MESH]Procoagulatio, hypercoagulatio es fibrinolysis "shut down" kimutatasa (epmc).pdf DeepDyve Pubget Overpricing