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10.1097/CCM.0000000000004457

http://scihub22266oqcxt.onion/10.1097/CCM.0000000000004457
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32452888!7255393!32452888
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suck abstract from ncbi


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pmid32452888      Crit+Care+Med 2020 ; 48 (9): e799-e804
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  • ICU and Ventilator Mortality Among Critically Ill Adults With Coronavirus Disease 2019 #MMPMID32452888
  • Auld SC; Caridi-Scheible M; Blum JM; Robichaux C; Kraft C; Jacob JT; Jabaley CS; Carpenter D; Kaplow R; Hernandez-Romieu AC; Adelman MW; Martin GS; Coopersmith CM; Murphy DJ
  • Crit Care Med 2020[Sep]; 48 (9): e799-e804 PMID32452888show ga
  • OBJECTIVES: To determine mortality rates among adults with critical illness from coronavirus disease 2019. DESIGN: Observational cohort study of patients admitted from March 6, 2020, to April 17, 2020. SETTING: Six coronavirus disease 2019 designated ICUs at three hospitals within an academic health center network in Atlanta, Georgia, United States. PATIENTS: Adults greater than or equal to 18 years old with confirmed severe acute respiratory syndrome-CoV-2 disease who were admitted to an ICU during the study period. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among 217 critically ill patients, mortality for those who required mechanical ventilation was 35.7% (59/165), with 4.8% of patients (8/165) still on the ventilator at the time of this report. Overall mortality to date in this critically ill cohort is 30.9% (67/217) and 60.4% (131/217) patients have survived to hospital discharge. Mortality was significantly associated with older age, lower body mass index, chronic renal disease, higher Sequential Organ Failure Assessment score, lower PaO2/FIO2 ratio, higher D-dimer, higher C-reactive protein, and receipt of mechanical ventilation, vasopressors, renal replacement therapy, or vasodilator therapy. CONCLUSIONS: Despite multiple reports of mortality rates exceeding 50% among critically ill adults with coronavirus disease 2019, particularly among those requiring mechanical ventilation, our early experience indicates that many patients survive their critical illness.
  • |*Betacoronavirus[MESH]
  • |*Respiration, Artificial[MESH]
  • |Aged[MESH]
  • |COVID-19[MESH]
  • |Cohort Studies[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/complications/*mortality/therapy[MESH]
  • |Critical Illness[MESH]
  • |Female[MESH]
  • |Georgia/epidemiology[MESH]
  • |Hospital Mortality[MESH]
  • |Humans[MESH]
  • |Intensive Care Units[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Organ Dysfunction Scores[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/*mortality/therapy[MESH]
  • |Respiratory Distress Syndrome/etiology/*mortality/therapy[MESH]
  • |SARS-CoV-2[MESH]


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