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10.1016/j.virol.2020.04.011

http://scihub22266oqcxt.onion/10.1016/j.virol.2020.04.011
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32452410!7192122!32452410
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suck abstract from ncbi


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pmid32452410      Virology 2020 ; 546 (ä): 122-126
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  • Association of viral load with serum biomakers among COVID-19 cases #MMPMID32452410
  • Shi F; Wu T; Zhu X; Ge Y; Zeng X; Chi Y; Du X; Zhu L; Zhu F; Zhu B; Cui L; Wu B
  • Virology 2020[Jul]; 546 (ä): 122-126 PMID32452410show ga
  • Since SARS-CoV-2 spreads rapidly around the world, data have been needed on the natural fluctuation of viral load and clinical indicators associated with it. We measured and compared viral loads of SARS-CoV-2 from pharyngeal swab, IgM anti-SARS-CoV-2, CRP and SAA from serum of 114 COVID-19 patients on admission. Positive rates of IgM anti-SARS-CoV-2, CRP and SAA were 80.7%, 36% and 75.4% respectively. Among IgM-positive patients, viral loads showed different trends among cases with different severity, While viral loads of IgM-negative patients tended to increase along with the time after onset. As the worsening of severity, the positive rates of CRP and SAA also showed trends of increase. Different CRP/SAA type showed associations with viral loads in patients in different severity and different time after onset. Combination of the IgM and CRP/SAA with time after onset and severity may give suggestions on the viral load and condition judgment of COVID-19 patients.
  • |*Viral Load[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Antibodies, Viral/*blood[MESH]
  • |Betacoronavirus[MESH]
  • |Biomarkers/blood[MESH]
  • |C-Reactive Protein/analysis[MESH]
  • |COVID-19[MESH]
  • |Child[MESH]
  • |Coronavirus Infections/blood/*diagnosis[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunoglobulin M/*blood[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pharynx/virology[MESH]
  • |Pneumonia, Viral/blood/*diagnosis[MESH]
  • |SARS-CoV-2[MESH]
  • |Serum Amyloid A Protein/analysis[MESH]


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