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10.1177/0194599820931793

http://scihub22266oqcxt.onion/10.1177/0194599820931793
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32450754!ä!32450754

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suck abstract from ncbi


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pmid32450754      Otolaryngol+Head+Neck+Surg 2020 ; 163 (3): 459-461
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  • Inappropriate Nasopharyngeal Sampling for SARS-CoV-2 Detection Is a Relevant Cause of False-Negative Reports #MMPMID32450754
  • Piras A; Rizzo D; Uzzau S; De Riu G; Rubino S; Bussu F
  • Otolaryngol Head Neck Surg 2020[Sep]; 163 (3): 459-461 PMID32450754show ga
  • Reverse transcriptase polymerase chain reaction (RT-PCR) detection of SARS-CoV-2 mRNA on nasopharyngeal swab is the standard for diagnosing active COVID-19 disease in asymptomatic cases and in symptomatic patients without the typical radiologic findings. For the present COVID-19 outbreak in Italy, we describe 4 symptomatic patients with negative RT-PCR results at the first nasopharyngeal swab, which became positive when collected a few hours later by an otolaryngologist. All the patients showed nasal obstruction. The present report suggests that inadequate nasopharyngeal sampling performed by untrained operators in the presence of nasal obstruction can be a relevant case of false-negative findings at RT-PCR, with a clear negative impact on the efforts to contain the current outbreak.
  • |*Clinical Competence[MESH]
  • |Aged[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*diagnosis[MESH]
  • |False Negative Reactions[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Italy[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nasal Obstruction/complications[MESH]
  • |Nasopharynx/*virology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]


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