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10.1016/j.phrs.2020.104946 http://scihub22266oqcxt.onion/10.1016/j.phrs.2020.104946 32450346!7244444!32450346     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pharmacol+Res 2020 ; 159 (ä): 104946 Nephropedia Template TP {{tp|p=32450346|t=2020. Biochemical indicators of coronavirus disease 2019 exacerbation and the clinical implications |pdf=|usr=}}{{32450346}} gab.com Text Biochemical indicators of coronavirus disease 2019 exacerbation and the clinical implications JO: Pharmacol Res http://www.kidney.de/pget.php?&tw=1&pmid=32450346 #FOAvip Coronavirus Disease 2019 (COVID-19) has sparked a global pandemic, affecting more than 4 million people worldwide. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause acute lung injury (ALI) and even acute respiratory distress syndrome (ARDS); with a fatality of 7.0 %. Accumulating evidence suggested that the progression of COVID-19 is associated with lymphopenia and excessive inflammation, and a subset of severe cases might exhibit cytokine storm triggered by secondary hemophagocytic lymphohistiocytosis (sHLH). Furthermore, secondary bacterial infection may contribute to the exacerbation of COVID-19. We recommend using both IL-10 and IL-6 as the indicators of cytokine storm, and monitoring the elevation of procalcitonin (PCT) as an alert for initiating antibacterial agents. Understanding the dynamic progression of SARS-CoV-2 infection is crucial to determine an effective treatment strategy to reduce the rising mortality of this global pandemic. Twit Text FOAVip Biochemical indicators of coronavirus disease 2019 exacerbation and the clinical implications ????Pharmacol Res http://www.kidney.de/pget.php?&tw=1&pmid=32450346 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32450346 #FOAvip English Wikipedia <ref>{{Cite pmid|32450346}}</ref> Biochemical indicators of coronavirus disease 2019 exacerbation and the clinical implications #MMPMID32450346 An PJ; Zhu YZ; Yang LP Pharmacol Res 2020[Sep]; 159 (ä): 104946 PMID32450346show ga Coronavirus Disease 2019 (COVID-19) has sparked a global pandemic, affecting more than 4 million people worldwide. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause acute lung injury (ALI) and even acute respiratory distress syndrome (ARDS); with a fatality of 7.0 %. Accumulating evidence suggested that the progression of COVID-19 is associated with lymphopenia and excessive inflammation, and a subset of severe cases might exhibit cytokine storm triggered by secondary hemophagocytic lymphohistiocytosis (sHLH). Furthermore, secondary bacterial infection may contribute to the exacerbation of COVID-19. We recommend using both IL-10 and IL-6 as the indicators of cytokine storm, and monitoring the elevation of procalcitonin (PCT) as an alert for initiating antibacterial agents. Understanding the dynamic progression of SARS-CoV-2 infection is crucial to determine an effective treatment strategy to reduce the rising mortality of this global pandemic. |*Betacoronavirus[MESH] |*Pandemics[MESH] |Biomarkers/blood[MESH] |COVID-19[MESH] |Coronavirus Infections/*blood/etiology/immunology[MESH] |Cytokines/blood[MESH] |Disease Progression[MESH] |Humans[MESH] |Interleukin-10/blood[MESH] |Interleukin-6/blood[MESH] |Lymphopenia/etiology/immunology[MESH] |Pneumonia, Viral/*blood/etiology/immunology[MESH] |Procalcitonin/blood[MESH]Biochemical indicators of coronavirus disease 2019 exacerbation and th(epmc).pdf DeepDyve Pubget Overpricing