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10.1111/ene.14361

http://scihub22266oqcxt.onion/10.1111/ene.14361
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32449248!7283788!32449248
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suck abstract from ncbi


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pmid32449248      Eur+J+Neurol 2020 ; 27 (9): 1748-1750
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  • COVID-19 and herpes zoster co-infection presenting with trigeminal neuropathy #MMPMID32449248
  • Ferreira ACAF; Romao TT; Macedo YS; Pupe C; Nascimento OJM
  • Eur J Neurol 2020[Sep]; 27 (9): 1748-1750 PMID32449248show ga
  • BACKGROUND: Varicella-zoster virus (VZV) is a human neurotropic virus that remains in a latent state within ganglionic neurons throughout the entire neuroaxis after the primary infection. When herpes zoster (HZ) leads to trigeminal involvement, the ophthalmic division is the most implicated. COVID-19 has emerged as a viral cause of severe acute respiratory syndrome that has spread all over the world in the last months. Co-infection with COVID-19 and other viruses has been reported, but sparsely, and involving the respiratory viruses. METHODS: The case of a co-infection of COVID-19 with VZV is reported, and the literature reviewed. RESULTS: A 39-year-old immunocompetent man presented with oligosymptomatic infection with COVID-19, which evolved to left facial HZ, affecting the three divisions of the trigeminal nerve. The co-infection was remotely registered, being the respiratory viruses, especially influenza, the most commonly cited association. However, the present case illustrates the emergence of a latent virus infection, which might be favored by the inflammatory response to the former agent (COVID-19). This reaction ascended from the nasal cavity, where trigeminal branches are also placed. CONCLUSIONS: The emergence of latent VZV infection in this rare presentation might illustrate an effect, at least locally, of COVID-19. This virus possibly induced a retrograde reactivation of VZV in a young immunocompetent patient.
  • |Adult[MESH]
  • |COVID-19/*complications[MESH]
  • |Coinfection[MESH]
  • |Herpes Zoster/*complications[MESH]
  • |Humans[MESH]
  • |Male[MESH]


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