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Successful recovery from severe COVID-19 pneumonia after kidney transplantation: The interplay between immunosuppression and novel therapy including tocilizumab #MMPMID32449235
Lauterio A; Valsecchi M; Santambrogio S; De Carlis R; Merli M; Calini A; Centonze L; Buscemi V; Bottiroli M; Puoti M; Fumagalli R; De Carlis L
Transpl Infect Dis 2020[Oct]; 22 (5): e13334 PMID32449235show ga
Although immunosuppressed patients may be more prone to SARS-CoV-2 infection with atypical presentation, long-term immunosuppression therapy may provide some sort of protection for severe clinical complications of COVID-19. The interaction between immunosuppression and new antiviral drugs in the treatment of transplanted patients contracting COVID-19 has not yet been fully investigated. Moreover, data regarding the optimal management of these patients are still very limited. We report a case of the successful recovery from severe COVID-19 of a kidney-transplanted patient treated with hydroxychloroquine, lopinavir/ritonavir, steroid, and tocilizumab.