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10.1111/febs.15375

http://scihub22266oqcxt.onion/10.1111/febs.15375
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32446285!7283703!32446285
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suck abstract from ncbi


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pmid32446285      FEBS+J 2020 ; 287 (17): 3633-3650
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  • A Guide to COVID-19: a global pandemic caused by the novel coronavirus SARS-CoV-2 #MMPMID32446285
  • Atzrodt CL; Maknojia I; McCarthy RDP; Oldfield TM; Po J; Ta KTL; Stepp HE; Clements TP
  • FEBS J 2020[Sep]; 287 (17): 3633-3650 PMID32446285show ga
  • The emergence of the SARS-CoV-2 strain of the human coronavirus has thrown the world into the midst of a new pandemic. In the human body, the virus causes COVID-19, a disease characterized by shortness of breath, fever, and pneumonia, which can be fatal in vulnerable individuals. SARS-CoV-2 has characteristics of past human coronaviruses, with close genomic similarities to SARS-CoV, the virus that causes the disease SARS. Like these related coronaviruses, SARS-CoV-2 is transmitted through the inhalation of droplets and interaction with contaminated surfaces. Across the world, laboratories are developing candidate vaccines for the virus - with vaccine trials underway in the United States and the United Kingdom - and considering various drugs for possible treatments and prophylaxis. Here, we provide an overview of SARS-CoV-2 by analyzing its virology, epidemiology, and modes of transmission while examining the current progress of testing procedures and possible treatments through drugs and vaccines.
  • |*Pandemics[MESH]
  • |Adenosine Monophosphate/analogs & derivatives/therapeutic use[MESH]
  • |Alanine/analogs & derivatives/therapeutic use[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |COVID-19 Testing/methods[MESH]
  • |COVID-19 Vaccines/therapeutic use[MESH]
  • |COVID-19/*epidemiology/immunology/pathology[MESH]
  • |Coronavirus Infections/drug therapy/*epidemiology/immunology/pathology[MESH]
  • |Drug Combinations[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/therapeutic use[MESH]
  • |Interferon beta-1a/therapeutic use[MESH]
  • |Lopinavir/therapeutic use[MESH]
  • |Middle East Respiratory Syndrome Coronavirus/immunology/pathogenicity[MESH]
  • |Respiration, Artificial/methods[MESH]
  • |Ritonavir/therapeutic use[MESH]
  • |SARS-CoV-2/drug effects/immunology/*pathogenicity[MESH]
  • |Severe Acute Respiratory Syndrome/drug therapy/*epidemiology/immunology/pathology[MESH]
  • |Severe acute respiratory syndrome-related coronavirus/immunology/pathogenicity[MESH]


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