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10.1111/pde.14246 http://scihub22266oqcxt.onion/10.1111/pde.14246 32445583!7283638!32445583     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pediatr+Dermatol 2020 ; 37 (3): 442-446 Nephropedia Template TP {{tp|p=32445583|t=2020. Erythema multiforme-like lesions in children and COVID-19 |pdf=|usr=}}{{32445583}} gab.com Text Erythema multiforme-like lesions in children and COVID-19 JO: Pediatr Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=32445583 #FOAvip During examination of cases of chilblains in children and adolescents, we identified four patients who also showed skin lesions similar to erythema multiforme (EM). They had no other known triggers for EM. One of them had a positive PCR for SARS-CoV-2, while the other three were negative. Skin biopsies from two patients showed features not typical of EM, such as deep perivascular and perieccrine infiltrate and absence of necrosis of keratinocytes. Immunohistochemistry for SARS-CoV/SARS-CoV-2 spike protein showed granular positivity in endothelial cells and epithelial cells of eccrine glands in both biopsies. All patients had an excellent outcome, and had minimal or no systemic symptoms. The coincidence of EM, a condition commonly related to viruses, and chilblains in the setting of COVID-19, and the positivity for SARS-CoV/SARS-CoV-2 spike protein by immunohistochemistry strongly suggest a link between EM-like lesions and SARS-CoV-2. Twit Text FOAVip Erythema multiforme-like lesions in children and COVID-19 ????Pediatr Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=32445583 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32445583 #FOAvip English Wikipedia <ref>{{Cite pmid|32445583}}</ref> Erythema multiforme-like lesions in children and COVID-19 #MMPMID32445583 Torrelo A; Andina D; Santonja C; Noguera-Morel L; Bascuas-Arribas M; Gaitero-Tristan J; Alonso-Cadenas JA; Escalada-Pellitero S; Hernandez-Martin A; de la Torre-Espi M; Colmenero I Pediatr Dermatol 2020[May]; 37 (3): 442-446 PMID32445583show ga During examination of cases of chilblains in children and adolescents, we identified four patients who also showed skin lesions similar to erythema multiforme (EM). They had no other known triggers for EM. One of them had a positive PCR for SARS-CoV-2, while the other three were negative. Skin biopsies from two patients showed features not typical of EM, such as deep perivascular and perieccrine infiltrate and absence of necrosis of keratinocytes. Immunohistochemistry for SARS-CoV/SARS-CoV-2 spike protein showed granular positivity in endothelial cells and epithelial cells of eccrine glands in both biopsies. All patients had an excellent outcome, and had minimal or no systemic symptoms. The coincidence of EM, a condition commonly related to viruses, and chilblains in the setting of COVID-19, and the positivity for SARS-CoV/SARS-CoV-2 spike protein by immunohistochemistry strongly suggest a link between EM-like lesions and SARS-CoV-2. |*Betacoronavirus[MESH] |Adolescent[MESH] |COVID-19[MESH] |Child[MESH] |Coronavirus Infections/*complications/*pathology[MESH] |Erythema Multiforme/*diagnosis/*virology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Pandemics[MESH] |Pneumonia, Viral/*complications/*pathology[MESH]Erythema multiforme-like lesions in children and COVID-19 (epmc).pdf DeepDyve Pubget Overpricing