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10.1093/cid/ciaa641 http://scihub22266oqcxt.onion/10.1093/cid/ciaa641 32445579!7314209!32445579     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Infect+Dis 2020 ; 71 (16): 2174-2179 Nephropedia Template TP {{tp|p=32445579|t=2020. Prognostic Value of C-Reactive Protein in Patients With Coronavirus 2019 |pdf=|usr=}}{{32445579}} gab.com Text Prognostic Value of C-Reactive Protein in Patients With Coronavirus 2019 JO: Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32445579 #FOAvip BACKGROUND: An elevated serum C-reactive protein (CRP) level was observed in most patients with coronavirus disease 2019 (COVID-19). METHODS: Data for COVID-19 patients with clinical outcome in a designated hospital in Wuhan, China, were retrospectively collected and analyzed from 30 January 2020 to 20 February 2020. The prognostic value of admission CRP was evaluated in patients with COVID-19. RESULTS: Of 298 patients enrolled, 84 died and 214 recovered. Most nonsurvivors were male, older, or with chronic diseases. Compared with survivors, nonsurvivors showed significantly elevated white blood cell and neutrophil counts, neutrophil to lymphocyte ratio (NLR), systemic immune inflammation index (defined by platelet count multiplied by NLR), CRP, procalcitonin, and D-dimer and showed decreased red blood cell, lymphocyte, and platelet counts. Age, neutrophil count, platelet count, and CRP were identified as independent predictors of adverse outcome. The area under the receiver operating characteristic (ROC) curve (AUC) of CRP (0.896) was significantly higher than that of age (0.833), neutrophil count (0.820), and platelet count (0.678) in outcome prediction (all P < .05). With a cutoff value of 41.4, CRP exhibited sensitivity of 90.5%, specificity of 77.6%, positive predictive value of 61.3%, and negative predictive value of 95.4%. CRP was also an independent discriminator of severe/critical illness on admission with an AUC (0.783) comparable to age (0.828) and neutrophil count (0.729) (both P > .05). CONCLUSIONS: In patients with COVID-19, admission CRP correlated with disease severity and tended to be a good predictor of adverse outcome. Twit Text FOAVip Prognostic Value of C-Reactive Protein in Patients With Coronavirus 2019 ????Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32445579 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32445579 #FOAvip English Wikipedia <ref>{{Cite pmid|32445579}}</ref> Prognostic Value of C-Reactive Protein in Patients With Coronavirus 2019 #MMPMID32445579 Luo X; Zhou W; Yan X; Guo T; Wang B; Xia H; Ye L; Xiong J; Jiang Z; Liu Y; Zhang B; Yang W Clin Infect Dis 2020[Nov]; 71 (16): 2174-2179 PMID32445579show ga BACKGROUND: An elevated serum C-reactive protein (CRP) level was observed in most patients with coronavirus disease 2019 (COVID-19). METHODS: Data for COVID-19 patients with clinical outcome in a designated hospital in Wuhan, China, were retrospectively collected and analyzed from 30 January 2020 to 20 February 2020. The prognostic value of admission CRP was evaluated in patients with COVID-19. RESULTS: Of 298 patients enrolled, 84 died and 214 recovered. Most nonsurvivors were male, older, or with chronic diseases. Compared with survivors, nonsurvivors showed significantly elevated white blood cell and neutrophil counts, neutrophil to lymphocyte ratio (NLR), systemic immune inflammation index (defined by platelet count multiplied by NLR), CRP, procalcitonin, and D-dimer and showed decreased red blood cell, lymphocyte, and platelet counts. Age, neutrophil count, platelet count, and CRP were identified as independent predictors of adverse outcome. The area under the receiver operating characteristic (ROC) curve (AUC) of CRP (0.896) was significantly higher than that of age (0.833), neutrophil count (0.820), and platelet count (0.678) in outcome prediction (all P < .05). With a cutoff value of 41.4, CRP exhibited sensitivity of 90.5%, specificity of 77.6%, positive predictive value of 61.3%, and negative predictive value of 95.4%. CRP was also an independent discriminator of severe/critical illness on admission with an AUC (0.783) comparable to age (0.828) and neutrophil count (0.729) (both P > .05). CONCLUSIONS: In patients with COVID-19, admission CRP correlated with disease severity and tended to be a good predictor of adverse outcome. |C-Reactive Protein/metabolism[MESH] |COVID-19/*metabolism/pathology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Pandemics[MESH] |Prognosis[MESH] |ROC Curve[MESH]Prognostic Value of C-Reactive Protein in Patients With Coronavirus 20(epmc).pdf DeepDyve Pubget Overpricing