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10.1002/cpt.1922

http://scihub22266oqcxt.onion/10.1002/cpt.1922
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32445484!7283813!32445484
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suck abstract from ncbi


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pmid32445484      Clin+Pharmacol+Ther 2020 ; 108 (5): 921-923
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  • A Real-World Evidence Framework for Optimizing Dosing in All Patients With COVID-19 #MMPMID32445484
  • Peck RW; Weiner D; Cook J; Robert Powell J
  • Clin Pharmacol Ther 2020[Nov]; 108 (5): 921-923 PMID32445484show ga
  • Potential treatments for coronavirus disease 2019 (COVID-19) are being investigated at unprecedented speed, and successful treatments will rapidly be used in tens or hundreds of thousands of patients. To ensure safe and effective use in all those patents it is essential also to develop, at unprecedented speed, a means to provide frequently updated, optimal dosing information for all patient subgroups. Success will require immediate collaboration between drug developers, academics, and regulators.
  • |*Antiviral Agents/pharmacokinetics/therapeutic use[MESH]
  • |*Coronavirus Infections/drug therapy/epidemiology[MESH]
  • |*Dose-Response Relationship, Drug[MESH]
  • |*Drug Development/methods/standards[MESH]
  • |*Drug Repositioning/methods/standards[MESH]
  • |*Drug-Related Side Effects and Adverse Reactions/blood/prevention & control[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral/drug therapy/epidemiology[MESH]
  • |Betacoronavirus/drug effects[MESH]
  • |Biological Availability[MESH]
  • |Biomarkers, Pharmacological/analysis[MESH]
  • |COVID-19[MESH]
  • |Drug Dosage Calculations[MESH]
  • |Drug Monitoring/standards[MESH]
  • |Humans[MESH]
  • |International Cooperation[MESH]
  • |SARS-CoV-2[MESH]


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