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10.1158/2159-8290.CD-20-0559

http://scihub22266oqcxt.onion/10.1158/2159-8290.CD-20-0559
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32444466!7357668!32444466
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suck abstract from ncbi


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pmid32444466      Cancer+Discov 2020 ; 10 (7): 916-921
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  • The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2 #MMPMID32444466
  • Tutuncuoglu B; Cakir M; Batra J; Bouhaddou M; Eckhardt M; Gordon DE; Krogan NJ
  • Cancer Discov 2020[Jul]; 10 (7): 916-921 PMID32444466show ga
  • The mapping of SARS-CoV-2 human protein-protein interactions by Gordon and colleagues revealed druggable targets that are hijacked by the virus. Here, we highlight several oncogenic pathways identified at the host-virus interface of SARS-CoV-2 to enable cancer biologists to apply their knowledge for rapid drug repurposing to treat COVID-19, and help inform the response to potential long-term complications of the disease.
  • |*Betacoronavirus[MESH]
  • |*Drug Repositioning[MESH]
  • |COVID-19[MESH]
  • |Cell Cycle[MESH]
  • |Coronavirus Infections/*drug therapy/genetics/metabolism/physiopathology[MESH]
  • |DNA Damage[MESH]
  • |Epigenomics[MESH]
  • |Humans[MESH]
  • |Neoplasm Proteins/*antagonists & inhibitors/drug effects[MESH]
  • |Neoplasms/*drug therapy/genetics/metabolism/physiopathology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy/genetics/metabolism/physiopathology[MESH]
  • |Protein Biosynthesis[MESH]


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