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10.1371/journal.ppat.1008536

http://scihub22266oqcxt.onion/10.1371/journal.ppat.1008536
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32442210!7244094!32442210
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suck abstract from ncbi

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  • The hallmarks of COVID-19 disease #MMPMID32442210
  • Tang D; Comish P; Kang R
  • PLoS Pathog 2020[May]; 16 (5): e1008536 PMID32442210show ga
  • Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that has caused a worldwide pandemic of the human respiratory illness COVID-19, resulting in a severe threat to public health and safety. Analysis of the genetic tree suggests that SARS-CoV-2 belongs to the same Betacoronavirus group as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Although the route for viral transmission remains a mystery, SARS-CoV-2 may have originated in an animal reservoir, likely that of bat. The clinical features of COVID-19, such as fever, cough, shortness of breath, and fatigue, are similar to those of many acute respiratory infections. There is currently no specific treatment for COVID-19, but antiviral therapy combined with supportive care is the main strategy. Here, we summarize recent progress in understanding the epidemiological, virological, and clinical characteristics of COVID-19 and discuss potential targets with existing drugs for the treatment of this emerging zoonotic disease.
  • |Animals[MESH]
  • |Betacoronavirus/classification[MESH]
  • |Coronavirus Infections/*epidemiology/physiopathology/*therapy[MESH]
  • |Genome, Viral[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology/physiopathology/*therapy[MESH]
  • |Zoonoses/epidemiology/virology[MESH]


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  • suck abstract from ncbi

    e1008536 5.16 2020