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10.1093/chemse/bjaa034

http://scihub22266oqcxt.onion/10.1093/chemse/bjaa034
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32441744!7314115!32441744
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suck abstract from ncbi


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pmid32441744      Chem+Senses 2020 ; ä (ä): ä
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  • Relationship between odor intensity estimates and COVID-19 prevalence prediction in a Swedish population #MMPMID32441744
  • Iravani B; Arshamian A; Ravia A; Mishor E; Snitz K; Shushan S; Roth Y; Perl O; Honigstein D; Weissgross R; Karagach S; Ernst G; Okamoto M; Mainen Z; Monteleone E; Dinnella C; Spinelli S; Marino-Sanchez F; Ferdenzi C; Smeets M; Touhara K; Bensafi M; Hummel T; Sobel N; Lundstrom JN
  • Chem Senses 2020[May]; ä (ä): ä PMID32441744show ga
  • In response to the COVID-19 pandemic, countries have implemented various strategies to reduce and slow the spread of the disease in the general population. For countries that have implemented restrictions on its population in a step-wise manner, monitoring of COVID-19 prevalence is of importance to guide decision on when to impose new, or when to abolish old, restrictions. We are here determining whether measures of odor intensity in a large sample can serve as one such measure. Online measures of how intense common household odors are perceived and symptoms of COVID-19 were collected from 2440 Swedes. Average odor intensity ratings were then compared to predicted COVID-19 population prevalence over time in the Swedish population and were found to closely track each other (r=-0.83). Moreover, we found that there was a large difference in rated intensity between individuals with and without COVID-19 symptoms and number of symptoms was related to odor intensity ratings. Finally, we found that individuals progressing from reporting no symptoms to subsequently reporting COVID-19 symptoms demonstrated a large drop in olfactory performance. These data suggest that measures of odor intensity, if obtained in a large and representative sample, can be used as an indicator of COVID-19 disease in the general population. Importantly, this simple measure could easily be implemented in countries without widespread access to COVID-19 testing or implemented as a fast early response before wide-spread testing can be facilitated.
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