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10.1016/j.ijid.2020.05.027

http://scihub22266oqcxt.onion/10.1016/j.ijid.2020.05.027
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32437932!7211646!32437932
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suck abstract from ncbi


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pmid32437932      Int+J+Infect+Dis 2020 ; 97 (ä): 174-176
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  • Usefulness of bronchoalveolar lavage in the management of patients presenting with lung infiltrates and suspect COVID-19-associated pneumonia: A case report #MMPMID32437932
  • Gualano G; Musso M; Mosti S; Mencarini P; Mastrobattista A; Pareo C; Zaccarelli M; Migliorisi P; Vittozzi P; Zumla A; Ippolito G; Palmieri F
  • Int J Infect Dis 2020[Aug]; 97 (ä): 174-176 PMID32437932show ga
  • OBJECTIVE: To report a clinical case of a patient with a compatible HRCT scan and two negative SARS-CoV-2 RNA upper respiratory tract specimens but with a confirmed viral infection by BAL (19 days after symptom onset). METHODS: Revision of a patient's clinical charts with COVID-19 admitted at INMI L. Spallanzani Hospital RESULTS: Two oropharyngeal swab tests of SARS-CoV-2 by qualitative real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay were performed at admission (17 days from symptoms onset) and a day apart and were found negative. BAL fluid collected 19 days after symptoms onset was positive for SARS-CoV-2. CONCLUSION: This case highlights importance of clinical suspicion of SARS-CoV-2 infection in diagnosis and infectivity assessment. We suggest collection of BAL fluid when consecutive nasopharyngeal swabs are negative, to confirm or exclude the diagnosis of COVID-19-associated pneumonia. Healthcare workers should perform aerosol-generating procedures in an adequately ventilated room and should wear adequate PPE.
  • |*Betacoronavirus/genetics[MESH]
  • |*Bronchoalveolar Lavage[MESH]
  • |Aged[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Clinical Laboratory Techniques[MESH]
  • |Coronavirus Infections/diagnosis/*therapy[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/diagnosis/*therapy[MESH]
  • |Real-Time Polymerase Chain Reaction[MESH]
  • |Respiratory System[MESH]


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