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10.1016/j.resp.2020.103455 http://scihub22266oqcxt.onion/10.1016/j.resp.2020.103455 32437877!7211757!32437877     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Respir+Physiol+Neurobiol 2020 ; 279 (ä): 103455 Nephropedia Template TP {{tp|p=32437877|t=2020. Distinct phenotypes require distinct respiratory management strategies in severe COVID-19 |pdf=|usr=}}{{32437877}} gab.com Text Distinct phenotypes require distinct respiratory management strategies in severe COVID-19 JO: Respir Physiol Neurobiol http://www.kidney.de/pget.php?&tw=1&pmid=32437877 #FOAvip Coronavirus disease 2019 (COVID-19) can cause severe respiratory failure requiring mechanical ventilation. The abnormalities observed on chest computed tomography (CT) and the clinical presentation of COVID-19 patients are not always like those of typical acute respiratory distress syndrome (ARDS) and can change over time. This manuscript aimed to provide brief guidance for respiratory management of COVID-19 patients before, during, and after mechanical ventilation, based on the recent literature and on our direct experience with this population. We identify that chest CT patterns in COVID-19 may be divided into three main phenotypes: 1) multiple, focal, possibly overperfused ground-glass opacities; 2) inhomogeneously distributed atelectasis; and 3) a patchy, ARDS-like pattern. Each phenotype can benefit from different treatments and ventilator settings. Also, peripheral macro- and microemboli are common, and attention should be paid to the risk of pulmonary embolism. We suggest use of personalized mechanical ventilation strategies based on respiratory mechanics and chest CT patterns. Further research is warranted to confirm our hypothesis. Twit Text FOAVip Distinct phenotypes require distinct respiratory management strategies in severe COVID-19 ????Respir Physiol Neurobiol http://www.kidney.de/pget.php?&tw=1&pmid=32437877 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32437877 #FOAvip English Wikipedia <ref>{{Cite pmid|32437877}}</ref> Distinct phenotypes require distinct respiratory management strategies in severe COVID-19 #MMPMID32437877 Robba C; Battaglini D; Ball L; Patroniti N; Loconte M; Brunetti I; Vena A; Giacobbe DR; Bassetti M; Rocco PRM; Pelosi P Respir Physiol Neurobiol 2020[Aug]; 279 (ä): 103455 PMID32437877show ga Coronavirus disease 2019 (COVID-19) can cause severe respiratory failure requiring mechanical ventilation. The abnormalities observed on chest computed tomography (CT) and the clinical presentation of COVID-19 patients are not always like those of typical acute respiratory distress syndrome (ARDS) and can change over time. This manuscript aimed to provide brief guidance for respiratory management of COVID-19 patients before, during, and after mechanical ventilation, based on the recent literature and on our direct experience with this population. We identify that chest CT patterns in COVID-19 may be divided into three main phenotypes: 1) multiple, focal, possibly overperfused ground-glass opacities; 2) inhomogeneously distributed atelectasis; and 3) a patchy, ARDS-like pattern. Each phenotype can benefit from different treatments and ventilator settings. Also, peripheral macro- and microemboli are common, and attention should be paid to the risk of pulmonary embolism. We suggest use of personalized mechanical ventilation strategies based on respiratory mechanics and chest CT patterns. Further research is warranted to confirm our hypothesis. |COVID-19[MESH] |Coronavirus Infections/complications/diagnostic imaging/pathology/*therapy[MESH] |Humans[MESH] |Lung/diagnostic imaging/*pathology[MESH] |Pandemics[MESH] |Pneumonia, Viral/complications/diagnostic imaging/pathology/*therapy[MESH] |Pulmonary Embolism/etiology/*therapy[MESH] |Respiration, Artificial/*methods/standards[MESH] |Respiratory Distress Syndrome/diagnostic imaging/etiology/pathology/*therapy[MESH]Distinct phenotypes require distinct respiratory management strategies(epmc).pdf DeepDyve Pubget Overpricing