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10.1016/j.lfs.2020.117765 http://scihub22266oqcxt.onion/10.1016/j.lfs.2020.117765 32437797!7207108!32437797     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Life+Sci 2020 ; 254 (ä): 117765 Nephropedia Template TP {{tp|p=32437797|t=2020. The current understanding and potential therapeutic options to combat COVID-19 |pdf=|usr=}}{{32437797}} gab.com Text The current understanding and potential therapeutic options to combat COVID-19 JO: Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=32437797 #FOAvip The ongoing wreaking global outbreak of the novel human beta coronavirus (CoV) pathogen was presumed to be from a seafood wholesale market in Wuhan, China, belongs to the Coronaviridae family in the Nidovirales order. The virus is highly contagious with potential human-human transmission which was named as the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread across six continents and emerged as a global pandemic in short span with alarming levels of spread and severity. This virus associated symptoms and infectious respiratory illness is designated as coronavirus disease 19 (COVID-19). The SARS-CoV-2 possesses enveloped club-like spike protein projections with positive-sense large RNA genome and has a unique replication strategy. This virus was believed to have zoonotic origin with genetical identity to bat and pangolin CoV. In the current review, we introduce a general overview about the human CoVs and the associated diseases, the origin, structure, replication and key clinical events that occur in the COVID-19 pathogenicity. Furthermore, we focused on possible therapeutic options such as repurposing drugs including antimalarials, antivirals, antiparasitic drugs, and anti-HIV drugs, as well as monoclonal antibodies, vaccines as potential treatment options. Also we have summarized the latest research progress on the usage of stem cell therapy, human convalescent serum, interferon's, in the treatment of COVID-19. Twit Text FOAVip The current understanding and potential therapeutic options to combat COVID-19 ????Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=32437797 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32437797 #FOAvip English Wikipedia <ref>{{Cite pmid|32437797}}</ref> The current understanding and potential therapeutic options to combat COVID-19 #MMPMID32437797 Pooladanda V; Thatikonda S; Godugu C Life Sci 2020[Aug]; 254 (ä): 117765 PMID32437797show ga The ongoing wreaking global outbreak of the novel human beta coronavirus (CoV) pathogen was presumed to be from a seafood wholesale market in Wuhan, China, belongs to the Coronaviridae family in the Nidovirales order. The virus is highly contagious with potential human-human transmission which was named as the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread across six continents and emerged as a global pandemic in short span with alarming levels of spread and severity. This virus associated symptoms and infectious respiratory illness is designated as coronavirus disease 19 (COVID-19). The SARS-CoV-2 possesses enveloped club-like spike protein projections with positive-sense large RNA genome and has a unique replication strategy. This virus was believed to have zoonotic origin with genetical identity to bat and pangolin CoV. In the current review, we introduce a general overview about the human CoVs and the associated diseases, the origin, structure, replication and key clinical events that occur in the COVID-19 pathogenicity. Furthermore, we focused on possible therapeutic options such as repurposing drugs including antimalarials, antivirals, antiparasitic drugs, and anti-HIV drugs, as well as monoclonal antibodies, vaccines as potential treatment options. Also we have summarized the latest research progress on the usage of stem cell therapy, human convalescent serum, interferon's, in the treatment of COVID-19. |Animals[MESH] |Betacoronavirus/isolation & purification[MESH] |COVID-19[MESH] |Coronavirus Infections/*epidemiology/*therapy/virology[MESH] |Pandemics/prevention & control[MESH] |Pneumonia, Viral/*epidemiology/*therapy/virology[MESH] |SARS-CoV-2[MESH]The current understanding and potential therapeutic options to combat (epmc).pdf DeepDyve Pubget Overpricing