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10.1016/j.jaci.2020.04.038 http://scihub22266oqcxt.onion/10.1016/j.jaci.2020.04.038 32437740!7211641!32437740     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Allergy+Clin+Immunol 2020 ; 146 (1): 101-109.e1 Nephropedia Template TP {{tp|p=32437740|t=2020. The immunologic status of newborns born to SARS-CoV-2-infected mothers in Wuhan, China |pdf=|usr=}}{{32437740}} gab.com Text The immunologic status of newborns born to SARS-CoV-2-infected mothers in Wuhan, China JO: J Allergy Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32437740 #FOAvip BACKGROUND: Immunologic dysfunction due to coronavirus disease 2019 (COVID-19) is closely related to clinical prognosis, and the inflammatory response of pregnant women may affect the directional differentiation and function of fetal immune cells. OBJECTIVE: We sought to analyze the immune status of newborns from mothers with COVID-19 in the third trimester. METHODS: Along with collecting the clinical data from 51 newborns and their respective mothers, we recorded the immunophenotypes and cytokine and immunoglobulin levels of the newborns. RESULTS: None of the 51 newborns showed fever or respiratory distress during hospitalization. Detection of severe acute respiratory syndrome coronavirus 2 nucleic acid in pharyngeal swabs was negative. Except for the low level of CD16-CD56 cells, the count and proportion of lymphocytes, CD3, CD4, CD8, and CD19 were all in the normal range. Moreover, the serum IgG and IgM levels were within the normal range, whereas IL-6 showed increased levels. There was no correlation between maternal COVID-19 duration and the lymphocyte subsets or cytokine levels (IFN-gamma, IL-2, IL-4, IL-6, IL-10, and TNF-alpha). There was a positive correlation between IL-6 and IL-10 levels and CD16-CD56 cells. One (1.96%) infant with an extremely elevated IL-6 concentration developed necrotizing enterocolitis in the third week after birth, and the remaining 50 infants did not show abnormal symptoms through the end of the follow-up period. CONCLUSIONS: COVID-19 in the third trimester did not significantly affect the cellular and humoral immunity of the fetus, and there was no evidence that the differentiation of lymphocyte subsets was seriously unbalanced. Twit Text FOAVip The immunologic status of newborns born to SARS-CoV-2-infected mothers in Wuhan, China ????J Allergy Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32437740 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32437740 #FOAvip English Wikipedia <ref>{{Cite pmid|32437740}}</ref> The immunologic status of newborns born to SARS-CoV-2-infected mothers in Wuhan, China #MMPMID32437740 Liu P; Zheng J; Yang P; Wang X; Wei C; Zhang S; Feng S; Lan J; He B; Zhao D; Li J; Zhang Y J Allergy Clin Immunol 2020[Jul]; 146 (1): 101-109.e1 PMID32437740show ga BACKGROUND: Immunologic dysfunction due to coronavirus disease 2019 (COVID-19) is closely related to clinical prognosis, and the inflammatory response of pregnant women may affect the directional differentiation and function of fetal immune cells. OBJECTIVE: We sought to analyze the immune status of newborns from mothers with COVID-19 in the third trimester. METHODS: Along with collecting the clinical data from 51 newborns and their respective mothers, we recorded the immunophenotypes and cytokine and immunoglobulin levels of the newborns. RESULTS: None of the 51 newborns showed fever or respiratory distress during hospitalization. Detection of severe acute respiratory syndrome coronavirus 2 nucleic acid in pharyngeal swabs was negative. Except for the low level of CD16-CD56 cells, the count and proportion of lymphocytes, CD3, CD4, CD8, and CD19 were all in the normal range. Moreover, the serum IgG and IgM levels were within the normal range, whereas IL-6 showed increased levels. There was no correlation between maternal COVID-19 duration and the lymphocyte subsets or cytokine levels (IFN-gamma, IL-2, IL-4, IL-6, IL-10, and TNF-alpha). There was a positive correlation between IL-6 and IL-10 levels and CD16-CD56 cells. One (1.96%) infant with an extremely elevated IL-6 concentration developed necrotizing enterocolitis in the third week after birth, and the remaining 50 infants did not show abnormal symptoms through the end of the follow-up period. CONCLUSIONS: COVID-19 in the third trimester did not significantly affect the cellular and humoral immunity of the fetus, and there was no evidence that the differentiation of lymphocyte subsets was seriously unbalanced. |Betacoronavirus[MESH] |COVID-19[MESH] |China[MESH] |Coronavirus Infections/*immunology[MESH] |Female[MESH] |Humans[MESH] |Infant, Newborn/*immunology[MESH] |Lymphocyte Subsets/immunology[MESH] |Male[MESH] |Pandemics[MESH] |Pneumonia, Viral/*immunology[MESH] |Pregnancy[MESH] |Pregnancy Complications, Infectious/*immunology[MESH] |Pregnancy Trimester, Third[MESH] |Prenatal Exposure Delayed Effects/*immunology[MESH]The immunologic status of newborns born to SARS-CoV-2-infected mothers(epmc).pdf DeepDyve Pubget Overpricing