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10.1002/jmv.26039 http://scihub22266oqcxt.onion/10.1002/jmv.26039 32437016!7280697!32437016     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Med+Virol 2020 ; 92 (11): 2536-2542 Nephropedia Template TP {{tp|p=32437016|t=2020. Obesity predisposes to the risk of higher mortality in young COVID-19 patients |pdf=|usr=}}{{32437016}} gab.com Text Obesity predisposes to the risk of higher mortality in young COVID-19 patients JO: J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=32437016 #FOAvip Although emerging data demonstrated mortality of young COVID-19 patients, no data have reported the risk factors of mortality for these young patients, and whether obesity is a risk for young COVID-19 patients remains unknown. We conducted a retrospective study including 13 young patients who died of COVID-19 and 40 matched survivors. Logistic regression was employed to characterize the risk factors of mortality in young obese COVID-19 patients. Most of the young deceased COVID-19 patients were mild cases at the time of admission, but the disease progressed rapidly featured by a higher severity of patchy shadows (100.00% vs 48.70%; P = .006), pleural thickening (61.50% vs 12.80%; P = .012), and mild pericardial effusion (76.90% vs 0.00%; P < .001). Most importantly, the deceased patients manifested higher body mass index (odds ratio [OR] = 1.354; 95% confidence interval [CI] = 1.075-1.704; P = .010), inflammation-related index C-reactive protein (OR = 1.014; 95% CI = 1.003-1.025; P = .014), cardiac injury biomarker hs-cTnI (OR = 1.420; 95% CI = 1.112-1.814; P = .005), and increased coagulation activity biomarker D-dimer (OR = 418.7; P = .047), as compared with that of survivors. Our data support that obesity could be a risk factor associated with high mortality in young COVID-19 patients, whereas aggravated inflammatory response, enhanced cardiac injury, and increased coagulation activity are likely to be the mechanisms contributing to the high mortality. Twit Text FOAVip Obesity predisposes to the risk of higher mortality in young COVID-19 patients ????J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=32437016 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32437016 #FOAvip English Wikipedia <ref>{{Cite pmid|32437016}}</ref> Obesity predisposes to the risk of higher mortality in young COVID-19 patients #MMPMID32437016 Zhang F; Xiong Y; Wei Y; Hu Y; Wang F; Li G; Liu K; Du R; Wang CY; Zhu W J Med Virol 2020[Nov]; 92 (11): 2536-2542 PMID32437016show ga Although emerging data demonstrated mortality of young COVID-19 patients, no data have reported the risk factors of mortality for these young patients, and whether obesity is a risk for young COVID-19 patients remains unknown. We conducted a retrospective study including 13 young patients who died of COVID-19 and 40 matched survivors. Logistic regression was employed to characterize the risk factors of mortality in young obese COVID-19 patients. Most of the young deceased COVID-19 patients were mild cases at the time of admission, but the disease progressed rapidly featured by a higher severity of patchy shadows (100.00% vs 48.70%; P = .006), pleural thickening (61.50% vs 12.80%; P = .012), and mild pericardial effusion (76.90% vs 0.00%; P < .001). Most importantly, the deceased patients manifested higher body mass index (odds ratio [OR] = 1.354; 95% confidence interval [CI] = 1.075-1.704; P = .010), inflammation-related index C-reactive protein (OR = 1.014; 95% CI = 1.003-1.025; P = .014), cardiac injury biomarker hs-cTnI (OR = 1.420; 95% CI = 1.112-1.814; P = .005), and increased coagulation activity biomarker D-dimer (OR = 418.7; P = .047), as compared with that of survivors. Our data support that obesity could be a risk factor associated with high mortality in young COVID-19 patients, whereas aggravated inflammatory response, enhanced cardiac injury, and increased coagulation activity are likely to be the mechanisms contributing to the high mortality. |*Body Mass Index[MESH] |*Disease Progression[MESH] |Adolescent[MESH] |Adult[MESH] |Age Factors[MESH] |COVID-19/diagnostic imaging/*mortality[MESH] |China[MESH] |Disease Susceptibility[MESH] |Female[MESH] |Hospitalization/statistics & numerical data[MESH] |Humans[MESH] |Inflammation/virology[MESH] |Male[MESH] |Middle Aged[MESH] |Obesity/*complications[MESH] |Odds Ratio[MESH] |Prognosis[MESH] |Retrospective Studies[MESH] |Risk Factors[MESH] |Tomography, X-Ray Computed[MESH]Obesity predisposes to the risk of higher mortality in young COVID-19 (epmc).pdf DeepDyve Pubget Overpricing