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10.1080/21505594.2020.1763637

http://scihub22266oqcxt.onion/10.1080/21505594.2020.1763637
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32434416!7250318!32434416
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suck abstract from ncbi


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pmid32434416      Virulence 2020 ; 11 (1): 486-488
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  • Mice with humanized-lungs and immune system - an idealized model for COVID-19 and other respiratory illness #MMPMID32434416
  • Pujhari S; Rasgon JL
  • Virulence 2020[Dec]; 11 (1): 486-488 PMID32434416show ga
  • Lack of an appropriate animal model to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent responsible for COVID-19 pandemic disease, represents a significant hurdle in the process of understanding disease biology and evaluating therapeutic and preventive candidates. It is time for public health agencies to revisit regulation on transplantation of human pluripotent stem cells for the possibility of the development of a humanized mice model with a humanized lung.
  • |*Disease Models, Animal[MESH]
  • |Animals[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*pathology[MESH]
  • |Humans[MESH]
  • |Mice[MESH]
  • |Pandemics[MESH]
  • |Pluripotent Stem Cells/*transplantation[MESH]
  • |Pneumonia, Viral/*pathology[MESH]
  • |Research/legislation & jurisprudence/standards/trends[MESH]
  • |Respiratory Tract Infections/*pathology[MESH]


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