Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.celrep.2020.107725 http://scihub22266oqcxt.onion/10.1016/j.celrep.2020.107725 32426212!7231734!32426212     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Rep 2020 ; 31 (9): 107725 Nephropedia Template TP {{tp|p=32426212|t=2020. Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections |pdf=|usr=}}{{32426212}} gab.com Text Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections JO: Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=32426212 #FOAvip The World Health Organization has declared the ongoing outbreak of COVID-19, which is caused by a novel coronavirus SARS-CoV-2, a pandemic. There is currently a lack of knowledge about the antibody response elicited from SARS-CoV-2 infection. One major immunological question concerns antigenic differences between SARS-CoV-2 and SARS-CoV. We address this question by analyzing plasma from patients infected by SARS-CoV-2 or SARS-CoV and from infected or immunized mice. Our results show that, although cross-reactivity in antibody binding to the spike protein is common, cross-neutralization of the live viruses may be rare, indicating the presence of a non-neutralizing antibody response to conserved epitopes in the spike. Whether such low or non-neutralizing antibody response leads to antibody-dependent disease enhancement needs to be addressed in the future. Overall, this study not only addresses a fundamental question regarding antigenicity differences between SARS-CoV-2 and SARS-CoV but also has implications for immunogen design and vaccine development. Twit Text FOAVip Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections ????Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=32426212 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32426212 #FOAvip English Wikipedia <ref>{{Cite pmid|32426212}}</ref> Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections #MMPMID32426212 Lv H; Wu NC; Tsang OT; Yuan M; Perera RAPM; Leung WS; So RTY; Chan JMC; Yip GK; Chik TSH; Wang Y; Choi CYC; Lin Y; Ng WW; Zhao J; Poon LLM; Peiris JSM; Wilson IA; Mok CKP Cell Rep 2020[Jun]; 31 (9): 107725 PMID32426212show ga The World Health Organization has declared the ongoing outbreak of COVID-19, which is caused by a novel coronavirus SARS-CoV-2, a pandemic. There is currently a lack of knowledge about the antibody response elicited from SARS-CoV-2 infection. One major immunological question concerns antigenic differences between SARS-CoV-2 and SARS-CoV. We address this question by analyzing plasma from patients infected by SARS-CoV-2 or SARS-CoV and from infected or immunized mice. Our results show that, although cross-reactivity in antibody binding to the spike protein is common, cross-neutralization of the live viruses may be rare, indicating the presence of a non-neutralizing antibody response to conserved epitopes in the spike. Whether such low or non-neutralizing antibody response leads to antibody-dependent disease enhancement needs to be addressed in the future. Overall, this study not only addresses a fundamental question regarding antigenicity differences between SARS-CoV-2 and SARS-CoV but also has implications for immunogen design and vaccine development. |Animals[MESH] |Antibodies, Neutralizing/immunology[MESH] |Antibodies, Viral/*immunology[MESH] |Antigens, Viral/*immunology[MESH] |Betacoronavirus/*immunology[MESH] |COVID-19[MESH] |Chlorocebus aethiops[MESH] |Coronavirus Infections/immunology/prevention & control[MESH] |Cross Reactions/immunology[MESH] |Enzyme-Linked Immunosorbent Assay[MESH] |Humans[MESH] |Male[MESH] |Mice[MESH] |Mice, Inbred BALB C[MESH] |Neutralization Tests[MESH] |Pandemics/prevention & control[MESH] |Pneumonia, Viral/immunology/prevention & control[MESH] |Receptors, Virus/metabolism[MESH] |SARS-CoV-2[MESH] |Severe Acute Respiratory Syndrome/immunology/prevention & control[MESH] |Severe acute respiratory syndrome-related coronavirus/*immunology[MESH] |Sf9 Cells[MESH] |Spike Glycoprotein, Coronavirus/*immunology[MESH] |Vero Cells[MESH]Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infec(epmc).pdf DeepDyve Pubget Overpricing