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10.1016/j.ijid.2020.05.045

http://scihub22266oqcxt.onion/10.1016/j.ijid.2020.05.045
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32425636!7231495!32425636
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suck abstract from ncbi


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pmid32425636      Int+J+Infect+Dis 2020 ; 96 (ä): 531-537
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  • Factors associated with the duration of viral shedding in adults with COVID-19 outside of Wuhan, China: a retrospective cohort study #MMPMID32425636
  • Qi L; Yang Y; Jiang D; Tu C; Wan L; Chen X; Li Z
  • Int J Infect Dis 2020[Jul]; 96 (ä): 531-537 PMID32425636show ga
  • OBJECTIVES: To investigate factors associated with the duration of viral shedding in patients with COVID-19, outside of Wuhan. METHODS: In this retrospective cohort study, patients with laboratory-confirmed COVID-19 in Changsha, China were included. Clinical characteristics, laboratory findings, treatment, and outcome were retrieved. Univariate and multivariate analyses were performed to explore potential factors. RESULTS: Overall, 147 patients with COVID-19 were included. The median duration of viral shedding (the number of days from symptoms onset until the successive negative detection of SARS-CoV-2 RNA) was 17 days (interquartile range [IQR], 12-21). Multivariate Logistic regression analysis indicated that the highest temperature at admission (odds ratio [OR], 5.200; 95% confidence interval [CI]: 1.190-22.726; p = 0.028), time from symptom onset to admission (OR, 1.740; 95% CI: 1.296-2.337; p < 0.001) and hospital length of stay (OR, 1.604; 95% CI: 1.262-2.040; p < 0.001) were risk factors for prolonged duration of viral shedding. CONCLUSIONS: This study, with a relatively large sample size, focused on the duration of viral shedding and related factors in patients with COVID-19, outside of Wuhan, China. Potential risk factors were identified and should be taken into consideration for the strategy of quarantining infected patients.
  • |*Virus Shedding[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Betacoronavirus[MESH]
  • |Body Temperature[MESH]
  • |COVID-19[MESH]
  • |China/epidemiology[MESH]
  • |Coronavirus Infections/diagnosis/epidemiology/*physiopathology[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Length of Stay[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Multivariate Analysis[MESH]
  • |Odds Ratio[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/diagnosis/epidemiology/*physiopathology[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]
  • |Time Factors[MESH]


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