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10.1016/j.amjcard.2020.04.054

http://scihub22266oqcxt.onion/10.1016/j.amjcard.2020.04.054
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32425199!7228893!32425199
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suck abstract from ncbi


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pmid32425199      Am+J+Cardiol 2020 ; 128 (ä): 147-150
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  • Cardiovascular Safety of Potential Drugs for the Treatment of Coronavirus Disease 2019 #MMPMID32425199
  • Aggarwal G; Henry BM; Aggarwal S; Bangalore S
  • Am J Cardiol 2020[Aug]; 128 (ä): 147-150 PMID32425199show ga
  • Coronavirus disease 2019 (COVID-19) has become a global pandemic. It is still uncontrolled in most countries and no therapies are currently available. Various drugs are under investigation for its treatment. The disease is known to have worse outcomes in patients who have underlying cardiovascular disease. Chloroquine/hydroxychloroquine, azithromycin, remdesivir and lopinavir/ritonavir are currently being studied in trials and show some promise. Conduction disorders, heart failure, and mortality have been reported with the use of these drugs. It is important to have knowledge of potential cardiotoxic effects of these drugs before using them for COVID-19 patients for better allocation of healthcare resources and improvement in clinical outcomes.
  • |*Betacoronavirus[MESH]
  • |Adenosine Monophosphate/administration & dosage/adverse effects/analogs & derivatives[MESH]
  • |Alanine/administration & dosage/adverse effects/analogs & derivatives[MESH]
  • |Anti-Infective Agents/administration & dosage/*adverse effects[MESH]
  • |Azithromycin/administration & dosage/adverse effects[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Cardiovascular Diseases/*chemically induced[MESH]
  • |Coronavirus Infections/*drug therapy[MESH]
  • |Drug Combinations[MESH]
  • |Enzyme Inhibitors/administration & dosage/*adverse effects[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/administration & dosage/adverse effects[MESH]
  • |Lopinavir/therapeutic use[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy[MESH]
  • |Ritonavir/therapeutic use[MESH]


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