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10.1111/tan.13941 http://scihub22266oqcxt.onion/10.1111/tan.13941 32424945!7276866!32424945     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       HLA 2020 ; 96 (2): 194-196 Nephropedia Template TP {{tp|p=32424945|t=2020. Distribution of HLA allele frequencies in 82 Chinese individuals with coronavirus disease-2019 (COVID-19) |pdf=|usr=}}{{32424945}} gab.com Text Distribution of HLA allele frequencies in 82 Chinese individuals with coronavirus disease-2019 (COVID-19) JO: HLA http://www.kidney.de/pget.php?&tw=1&pmid=32424945 #FOAvip COVID-19 is a respiratory disease caused by a novel coronavirus and is currently a global pandemic. HLA variation is associated with COVID-19 because HLA plays a pivotal role in the immune response to pathogens. Here, 82 individuals with COVID-19 were genotyped for HLA-A, -B, -C, -DRB1, -DRB3/4/5, -DQA1, -DQB1, -DPA1, and -DPB1 loci using next-generation sequencing (NGS). Frequencies of the HLA-C*07:29, C*08:01G, B*15:27, B*40:06, DRB1*04:06, and DPB1*36:01 alleles were higher, while the frequencies of the DRB1*12:02 and DPB1*04:01 alleles were lower in COVID-19 patients than in the control population, with uncorrected statistical significance. Only HLA-C*07:29 and B*15:27 were significant when the corrected P-value was considered. These data suggested that some HLA alleles may be associated with the occurrence of COVID-19. Twit Text FOAVip Distribution of HLA allele frequencies in 82 Chinese individuals with coronavirus disease-2019 (COVID-19) ????HLA http://www.kidney.de/pget.php?&tw=1&pmid=32424945 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32424945 #FOAvip English Wikipedia <ref>{{Cite pmid|32424945}}</ref> Distribution of HLA allele frequencies in 82 Chinese individuals with coronavirus disease-2019 (COVID-19) #MMPMID32424945 Wang W; Zhang W; Zhang J; He J; Zhu F HLA 2020[Aug]; 96 (2): 194-196 PMID32424945show ga COVID-19 is a respiratory disease caused by a novel coronavirus and is currently a global pandemic. HLA variation is associated with COVID-19 because HLA plays a pivotal role in the immune response to pathogens. Here, 82 individuals with COVID-19 were genotyped for HLA-A, -B, -C, -DRB1, -DRB3/4/5, -DQA1, -DQB1, -DPA1, and -DPB1 loci using next-generation sequencing (NGS). Frequencies of the HLA-C*07:29, C*08:01G, B*15:27, B*40:06, DRB1*04:06, and DPB1*36:01 alleles were higher, while the frequencies of the DRB1*12:02 and DPB1*04:01 alleles were lower in COVID-19 patients than in the control population, with uncorrected statistical significance. Only HLA-C*07:29 and B*15:27 were significant when the corrected P-value was considered. These data suggested that some HLA alleles may be associated with the occurrence of COVID-19. |Alleles[MESH] |Asian People/genetics[MESH] |Betacoronavirus[MESH] |COVID-19[MESH] |China/epidemiology[MESH] |Coronavirus Infections/*genetics/immunology[MESH] |Gene Frequency[MESH] |Genotype[MESH] |HLA Antigens/*genetics[MESH] |Haplotypes[MESH] |High-Throughput Nucleotide Sequencing[MESH] |Humans[MESH] |Immune System[MESH] |Models, Statistical[MESH] |Pandemics[MESH] |Pneumonia, Viral/*genetics/immunology[MESH] |Polymorphism, Genetic[MESH]Distribution of HLA allele frequencies in 82 Chinese individuals with (epmc).pdf DeepDyve Pubget Overpricing