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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Infect+Chemother 2020 ; 26 (8): 851-853 Nephropedia Template TP
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Difficulty of downscaling the precautions for coronavirus disease-19 based on negative throat polymerase chain results in the early phase of infection #MMPMID32423700
Suzuki T; Kutsuna S; Nakamura K; Ide S; Moriyama Y; Saito S; Morioka S; Ishikane M; Kinoshita N; Hayakawa K; Ohmagari N
J Infect Chemother 2020[Aug]; 26 (8): 851-853 PMID32423700show ga
We here report a case of coronavirus disease-19 (COVID-19) in Japan in which the initial throat swab polymerase chain reaction result was negative The possibility of false-negative results in the early phase of disease suggest reconsideration of the feasibility of a community or national infection control framework to prevent transmission. We recommend establishing an alternative feasible system, such as self-isolation by contact history in non-endemic community and by symptoms in endemic community, not relying on the PCR examination, to minimize this ongoing COVID-19 outbreak. Further rapid accumulation of knowledge including incubation period, clinical course and types of transmission is warranted to control this outbreak.