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10.1016/j.jiac.2020.05.002

http://scihub22266oqcxt.onion/10.1016/j.jiac.2020.05.002
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suck abstract from ncbi


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pmid32423700      J+Infect+Chemother 2020 ; 26 (8): 851-853
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  • Difficulty of downscaling the precautions for coronavirus disease-19 based on negative throat polymerase chain results in the early phase of infection #MMPMID32423700
  • Suzuki T; Kutsuna S; Nakamura K; Ide S; Moriyama Y; Saito S; Morioka S; Ishikane M; Kinoshita N; Hayakawa K; Ohmagari N
  • J Infect Chemother 2020[Aug]; 26 (8): 851-853 PMID32423700show ga
  • We here report a case of coronavirus disease-19 (COVID-19) in Japan in which the initial throat swab polymerase chain reaction result was negative The possibility of false-negative results in the early phase of disease suggest reconsideration of the feasibility of a community or national infection control framework to prevent transmission. We recommend establishing an alternative feasible system, such as self-isolation by contact history in non-endemic community and by symptoms in endemic community, not relying on the PCR examination, to minimize this ongoing COVID-19 outbreak. Further rapid accumulation of knowledge including incubation period, clinical course and types of transmission is warranted to control this outbreak.
  • |*Clinical Laboratory Techniques[MESH]
  • |Betacoronavirus/genetics/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |China[MESH]
  • |Coronavirus Infections/complications/*diagnosis[MESH]
  • |False Negative Reactions[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Japan[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pharynx/*virology[MESH]
  • |Pneumonia, Viral/complications/diagnosis/*diagnostic imaging/virology[MESH]
  • |Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]


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