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10.1152/ajpendo.00183.2020

http://scihub22266oqcxt.onion/10.1152/ajpendo.00183.2020
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32421367!7276979!32421367
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suck abstract from ncbi


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pmid32421367      Am+J+Physiol+Endocrinol+Metab 2020 ; 318 (6): E878-E880
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  • Is there an impact of the COVID-19 pandemic on male fertility? The ACE2 connection #MMPMID32421367
  • Younis JS; Abassi Z; Skorecki K
  • Am J Physiol Endocrinol Metab 2020[Jun]; 318 (6): E878-E880 PMID32421367show ga
  • The viral pandemic of the coronavirus disease 2019 (COVID-19), generated by a novel mutated severe acute respiratory syndrome coronavirus (SARS-CoV-2), has become a serious worldwide public health emergency, evolving exponentially. While the main organ targeted in this disease is the lungs, other vital organs, such as the heart and kidney, may be implicated. The main host receptor of the SARS-CoV-2 is angiotensin converting enzyme 2 (ACE2), a major component of the renin-angiotensin-aldosterone system (RAAS). The ACE2 is also involved in testicular male regulation of steroidogenesis and spermatogenesis. As the SARS-CoV-2 may have the potential to infect the testis via ACE2 and adversely affect male reproductive system, it is essential to commence with targeted studies to learn from the current pandemic, with the possibility of preemptive intervention, depending on the findings and time course of the continuing pandemic.
  • |Angiotensin-Converting Enzyme 2[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*complications[MESH]
  • |Humans[MESH]
  • |Infertility, Male/*virology[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Peptidyl-Dipeptidase A/*physiology[MESH]
  • |Pneumonia, Viral/*complications[MESH]
  • |Receptors, Virus/physiology[MESH]
  • |Renin-Angiotensin System[MESH]
  • |SARS-CoV-2[MESH]
  • |Spermatogenesis[MESH]


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