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10.23750/abm.v91i2.9700

http://scihub22266oqcxt.onion/10.23750/abm.v91i2.9700
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32420947!7569626!32420947
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suck abstract from ncbi


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pmid32420947      Acta+Biomed 2020 ; 91 (2): 207-213
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  • Stop playing with data: there is no sound evidence that Bacille Calmette-Guerin may avoid SARS-CoV-2 infection (for now) #MMPMID32420947
  • Ricco M; Gualerzi G; Ranzieri S; Bragazzi NL
  • Acta Biomed 2020[May]; 91 (2): 207-213 PMID32420947show ga
  • Since the beginning of the COVID-19 epidemic, a possible explanation for the high heterogeneity of infection/mortality rates across involved countries was hinted in the prevalence of tuberculosis vaccination with Bacille Calmette-Guerin (BCG). A systematic review was therefore performed on May 2, 2020. A total of 13 articles were ultimately retrieved, 12 of them as preprint papers. All articles were ecological studies of low quality. Most of them did not include main confounding factors (i.e. demographic of the assessed countries, share of peo- ple residing in urban settings, etc.), and simply assessed the differences among incidence/mortality of COVID-19 with vaccination rates or by having vs. having not any vaccination policy for BCG. Even though all studies shared the very same information sources (i.e. international registries for BCG vaccination rates and open source data for COVID-19 epidemics), results were conflicting, with later studies apparently denying any true correlation between COVID-19 occurrence and BCG vaccination rates and/or policies. As a consequence, there is no sound evidence to recommend BCG vaccination for the prevention of COVID-19.
  • |*Betacoronavirus[MESH]
  • |BCG Vaccine/*immunology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/immunology/*prevention & control[MESH]
  • |Humans[MESH]
  • |Mycobacterium bovis/*immunology[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Pneumonia, Viral/immunology/*prevention & control[MESH]
  • |SARS-CoV-2[MESH]


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