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10.1016/j.clindermatol.2020.05.003

http://scihub22266oqcxt.onion/10.1016/j.clindermatol.2020.05.003
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32419721!7224642!32419721
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suck abstract from ncbi


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pmid32419721      Clin+Dermatol 2020 ; 38 (6): 775-780
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  • Evidence-based best practice advice for patients treated with systemic immunosuppressants in relation to COVID-19 #MMPMID32419721
  • Galimberti F; McBride J; Cronin M; Li Y; Fox J; Abrouk M; Herbst A; Kirsner RS
  • Clin Dermatol 2020[Nov]; 38 (6): 775-780 PMID32419721show ga
  • The emergence of the COVID-19 pandemic has led to significant uncertainty among physicians and patients about the safety of immunosuppressive medications used for the management of dermatologic conditions. We review available data on commonly used immunosuppressants and their effect on viral infections beyond COVID-19. Notably, the effect of some immunosuppressants on viruses related to SARS-CoV2, including SARS and MERS, has been previously investigated. In the absence of data on the effect of immunosuppressants on COVID-19, these data could be used to make clinical decisions on initiation and continuation of immunosuppressive medications during this pandemic. In summary, we recommend considering the discontinuation of oral Janus kinase (JAK) inhibitors and prednisone; considering the delay of rituximab infusion; and suggesting the careful continuation of cyclosporine, mycophenolate, azathioprine, methotrexate, and biologics in patients currently benefitting from such treatments.
  • |Azathioprine/therapeutic use[MESH]
  • |Biological Products/therapeutic use[MESH]
  • |COVID-19/*complications[MESH]
  • |Cyclosporine/therapeutic use[MESH]
  • |Evidence-Based Medicine[MESH]
  • |Humans[MESH]
  • |Immunosuppressive Agents/*therapeutic use[MESH]
  • |Janus Kinase Inhibitors/therapeutic use[MESH]
  • |Methotrexate/therapeutic use[MESH]
  • |Mycophenolic Acid/therapeutic use[MESH]
  • |Prednisone/therapeutic use[MESH]
  • |Rituximab/therapeutic use[MESH]
  • |SARS-CoV-2[MESH]
  • |Severe Acute Respiratory Syndrome/complications[MESH]


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