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10.1080/22221751.2020.1771219 http://scihub22266oqcxt.onion/10.1080/22221751.2020.1771219 32419639!7450259!32419639     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Emerg+Microbes+Infect 2020 ; 9 (1): 1233-1237 Nephropedia Template TP {{tp|p=32419639|t=2020. Viral loads in throat and anal swabs in children infected with SARS-CoV-2 |pdf=|usr=}}{{32419639}} gab.com Text Viral loads in throat and anal swabs in children infected with SARS-CoV-2 JO: Emerg Microbes Infect http://www.kidney.de/pget.php?&tw=1&pmid=32419639 #FOAvip Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay on anal swabs was recently reported to be persistently positive even after throat testing was negative during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, data about the consistent performance of RT-PCR assay on throat and anal swabs remain limited in paediatric patients. Here, we retrospectively reviewed RT-PCR-testing results of 212 paediatric patients with suspected SARS-CoV-2 infection at Wuhan Children's Hospital. The diagnostic potential of these two types of specimens showed significant difference (positive rate: 78.2% on throat swabs vs. 52.6% on anal swabs, McNemar Test P = 0.0091) and exhibited a weak positive consistency (Kappa value was 0.311, P < 0.0001) in paediatric patients. Furthermore, viral loads detected on both throat and anal swabs also showed no significant difference (P = 0.9511) and correlation (Pearson r = 0.0434, P = 0.8406), and exhibited an inconsistent kinetic change through the course of SARS-CoV-2 infection. Besides, viral loads in the throat and anal swabs were correlated with different types of immune states, immune-reactive phase, and the resolution phase/immunologic tolerance, respectively. These findings revealed that RT-PCR-testing on throat and anal swabs showed significant difference for monitoring SARS-CoV-2 infection and correlated with different immune state in paediatric patients. Twit Text FOAVip Viral loads in throat and anal swabs in children infected with SARS-CoV-2 ????Emerg Microbes Infect http://www.kidney.de/pget.php?&tw=1&pmid=32419639 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32419639 #FOAvip English Wikipedia <ref>{{Cite pmid|32419639}}</ref> Viral loads in throat and anal swabs in children infected with SARS-CoV-2 #MMPMID32419639 Yuan C; Zhu H; Yang Y; Cai X; Xiang F; Wu H; Yao C; Xiang Y; Xiao H Emerg Microbes Infect 2020[Dec]; 9 (1): 1233-1237 PMID32419639show ga Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay on anal swabs was recently reported to be persistently positive even after throat testing was negative during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, data about the consistent performance of RT-PCR assay on throat and anal swabs remain limited in paediatric patients. Here, we retrospectively reviewed RT-PCR-testing results of 212 paediatric patients with suspected SARS-CoV-2 infection at Wuhan Children's Hospital. The diagnostic potential of these two types of specimens showed significant difference (positive rate: 78.2% on throat swabs vs. 52.6% on anal swabs, McNemar Test P = 0.0091) and exhibited a weak positive consistency (Kappa value was 0.311, P < 0.0001) in paediatric patients. Furthermore, viral loads detected on both throat and anal swabs also showed no significant difference (P = 0.9511) and correlation (Pearson r = 0.0434, P = 0.8406), and exhibited an inconsistent kinetic change through the course of SARS-CoV-2 infection. Besides, viral loads in the throat and anal swabs were correlated with different types of immune states, immune-reactive phase, and the resolution phase/immunologic tolerance, respectively. These findings revealed that RT-PCR-testing on throat and anal swabs showed significant difference for monitoring SARS-CoV-2 infection and correlated with different immune state in paediatric patients. |*Viral Load[MESH] |Anal Canal/*virology[MESH] |Betacoronavirus/genetics/*isolation & purification[MESH] |COVID-19[MESH] |Child[MESH] |China/epidemiology[MESH] |Coronavirus Infections/diagnosis/epidemiology/*virology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Pandemics[MESH] |Pharynx/*virology[MESH] |Pneumonia, Viral/diagnosis/epidemiology/*virology[MESH] |Real-Time Polymerase Chain Reaction/standards[MESH] |Retrospective Studies[MESH]Viral loads in throat and anal swabs in children infected with SARS-Co(epmc).pdf DeepDyve Pubget Overpricing