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10.1016/j.lfs.2020.117775 http://scihub22266oqcxt.onion/10.1016/j.lfs.2020.117775 32418894!7211740!32418894     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Life+Sci 2020 ; 254 (ä): 117775 Nephropedia Template TP {{tp|p=32418894|t=2020. A systematic review on use of aminoquinolines for the therapeutic management of COVID-19: Efficacy, safety and clinical trials |pdf=|usr=}}{{32418894}} gab.com Text A systematic review on use of aminoquinolines for the therapeutic management of COVID-19: Efficacy, safety and clinical trials JO: Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=32418894 #FOAvip Recent global outbreak of the pandemic caused by coronavirus (COVID-19) emphasizes the urgent need for novel antiviral therapeutics. It can be supplemented by utilization of efficient and validated drug discovery approaches such as drug repurposing/repositioning. The well reported and clinically used anti-malarial aminoquinoline drugs (chloroquine and hydroxychloroquine) have shown potential to be repurposed to control the present pandemic by inhibition of COVID-19. The review elaborates the mechanism of action, safety (side effects, adverse effects, toxicity) and details of clinical trials for chloroquine and hydroxychloroquine to benefit the clinicians, medicinal chemist, pharmacologist actively involved in controlling the pandemic and to provide therapeutics for the treatment of COVID-19 infection. Twit Text FOAVip A systematic review on use of aminoquinolines for the therapeutic management of COVID-19: Efficacy, safety and clinical trials ????Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=32418894 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32418894 #FOAvip English Wikipedia <ref>{{Cite pmid|32418894}}</ref> A systematic review on use of aminoquinolines for the therapeutic management of COVID-19: Efficacy, safety and clinical trials #MMPMID32418894 Patil VM; Singhal S; Masand N Life Sci 2020[Aug]; 254 (ä): 117775 PMID32418894show ga Recent global outbreak of the pandemic caused by coronavirus (COVID-19) emphasizes the urgent need for novel antiviral therapeutics. It can be supplemented by utilization of efficient and validated drug discovery approaches such as drug repurposing/repositioning. The well reported and clinically used anti-malarial aminoquinoline drugs (chloroquine and hydroxychloroquine) have shown potential to be repurposed to control the present pandemic by inhibition of COVID-19. The review elaborates the mechanism of action, safety (side effects, adverse effects, toxicity) and details of clinical trials for chloroquine and hydroxychloroquine to benefit the clinicians, medicinal chemist, pharmacologist actively involved in controlling the pandemic and to provide therapeutics for the treatment of COVID-19 infection. |Aminoquinolines/*adverse effects/*therapeutic use[MESH] |Antiviral Agents/*adverse effects/*therapeutic use[MESH] |Betacoronavirus/drug effects[MESH] |COVID-19[MESH] |Chloroquine/adverse effects/therapeutic use[MESH] |Clinical Trials as Topic[MESH] |Coronavirus Infections/*drug therapy[MESH] |Drug Repositioning[MESH] |Humans[MESH] |Hydroxychloroquine/adverse effects/therapeutic use[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy[MESH] |Randomized Controlled Trials as Topic[MESH] |SARS-CoV-2[MESH]A systematic review on use of aminoquinolines for the therapeutic mana(epmc).pdf DeepDyve Pubget Overpricing