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10.1016/j.cytogfr.2020.05.002 http://scihub22266oqcxt.onion/10.1016/j.cytogfr.2020.05.002 32418715!7204669!32418715     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cytokine+Growth+Factor+Rev 2020 ; 53 (ä): 66-70 Nephropedia Template TP {{tp|p=32418715|t=2020. COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons |pdf=|usr=}}{{32418715}} gab.com Text COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons JO: Cytokine Growth Factor Rev http://www.kidney.de/pget.php?&tw=1&pmid=32418715 #FOAvip The outbreak of the novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) responsible for coronavirus disease 2019 (COVID-19) has developed into an unprecedented global pandemic. Clinical investigations in patients with COVID-19 has shown a strong upregulation of cytokine and interferon production in SARS-CoV2- induced pneumonia, with an associated cytokine storm syndrome. Thus, the identification of existing approved therapies with proven safety profiles to treat hyperinflammation is a critical unmet need in order to reduce COVI-19 associated mortality. To date, no specific therapeutic drugs or vaccines are available to treat COVID-19 patients. This review evaluates several options that have been proposed to control SARS-CoV2 hyperinflammation and cytokine storm, eincluding antiviral drugs, vaccines, small-molecules, monoclonal antibodies, oligonucleotides, peptides, and interferons (IFNs). Twit Text FOAVip COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons ????Cytokine Growth Factor Rev http://www.kidney.de/pget.php?&tw=1&pmid=32418715 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32418715 #FOAvip English Wikipedia <ref>{{Cite pmid|32418715}}</ref> COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons #MMPMID32418715 Nile SH; Nile A; Qiu J; Li L; Jia X; Kai G Cytokine Growth Factor Rev 2020[Jun]; 53 (ä): 66-70 PMID32418715show ga The outbreak of the novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) responsible for coronavirus disease 2019 (COVID-19) has developed into an unprecedented global pandemic. Clinical investigations in patients with COVID-19 has shown a strong upregulation of cytokine and interferon production in SARS-CoV2- induced pneumonia, with an associated cytokine storm syndrome. Thus, the identification of existing approved therapies with proven safety profiles to treat hyperinflammation is a critical unmet need in order to reduce COVI-19 associated mortality. To date, no specific therapeutic drugs or vaccines are available to treat COVID-19 patients. This review evaluates several options that have been proposed to control SARS-CoV2 hyperinflammation and cytokine storm, eincluding antiviral drugs, vaccines, small-molecules, monoclonal antibodies, oligonucleotides, peptides, and interferons (IFNs). |Adenosine Monophosphate/*analogs & derivatives/therapeutic use[MESH] |Alanine/*analogs & derivatives/therapeutic use[MESH] |Antibodies, Monoclonal/therapeutic use[MESH] |Antiviral Agents/*therapeutic use[MESH] |Betacoronavirus/*drug effects[MESH] |COVID-19[MESH] |Coronavirus Infections/*drug therapy/*pathology[MESH] |Cytokine Release Syndrome/drug therapy/pathology[MESH] |Cytokines/blood[MESH] |Drug Therapy, Combination[MESH] |Humans[MESH] |Inflammation/drug therapy/pathology[MESH] |Interferons/*therapeutic use[MESH] |Oligonucleotides/therapeutic use[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy/*pathology[MESH] |SARS-CoV-2[MESH]COVID-19: Pathogenesis, cytokine storm and therapeutic potential of in(epmc).pdf DeepDyve Pubget Overpricing