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10.1016/j.jcv.2020.104394

http://scihub22266oqcxt.onion/10.1016/j.jcv.2020.104394
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32416599!7189838!32416599
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suck abstract from ncbi


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pmid32416599      J+Clin+Virol 2020 ; 128 (ä): 104394
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  • Comparison of four new commercial serologic assays for determination of SARS-CoV-2 IgG #MMPMID32416599
  • Kruttgen A; Cornelissen CG; Dreher M; Hornef M; Imohl M; Kleines M
  • J Clin Virol 2020[Jul]; 128 (ä): 104394 PMID32416599show ga
  • BACKGROUND: Facing the ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is an urgent need for serological assays identifying individuals with past coronavirus disease 2019 (COVID-19). STUDY DESIGN: Our study is the first to compare four new commercially available assays using 75 sera from patients tested positive or negative by SARS-CoV-2 PCR: the anti SARS-CoV-2 ELISA (IgG) (Euroimmun, Germany), the EDI New Coronavirus COVID-19 IgG ELISA, (Epitope diagnostics (EDI), USA), the recomWell SARS-CoV-2 IgG ELISA (Mikrogen, Germany), and the SARS-CoV-2 Virachip IgG (Viramed, Germany). RESULTS: We found a sensitivity of 86.4 %, 100 %, 86.4 %, and 77.3 % and a specificity of 96,2 %, 88,7 %, 100 %, and 100 % for the Euroimmun assay, the EDI assay, the Mikrogen assay, and the Viramed assay, respectively. CONCLUSIONS: Commercially available SARS-CoV-2 IgG assays have a sufficient specificity and sensitivity for identifying individuals with past SARS-CoV-2 infection.
  • |*Pandemics[MESH]
  • |Antibodies, Viral/*blood[MESH]
  • |Betacoronavirus/*immunology[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques/*methods[MESH]
  • |Coronavirus Infections/*diagnosis/virology[MESH]
  • |Enzyme-Linked Immunosorbent Assay/methods[MESH]
  • |Germany[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G/*blood[MESH]
  • |Pneumonia, Viral/*diagnosis/virology[MESH]
  • |Reagent Kits, Diagnostic[MESH]
  • |SARS-CoV-2[MESH]


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