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10.1016/j.dsx.2020.04.050 http://scihub22266oqcxt.onion/10.1016/j.dsx.2020.04.050 32413819!7204679!32413819     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Diabetes+Metab+Syndr 2020 ; 14 (4): 561-565 Nephropedia Template TP {{tp|p=32413819|t=2020. Vitamin D concentrations and COVID-19 infection in UK Biobank |pdf=|usr=}}{{32413819}} gab.com Text Vitamin D concentrations and COVID-19 infection in UK Biobank JO: Diabetes Metab Syndr http://www.kidney.de/pget.php?&tw=1&pmid=32413819 #FOAvip BACKGROUND AND AIMS: COVID-19 and low levels of vitamin D appear to disproportionately affect black and minority ethnic individuals. We aimed to establish whether blood 25-hydroxyvitamin D (25(OH)D) concentration was associated with COVID-19 risk, and whether it explained the higher incidence of COVID-19 in black and South Asian people. METHODS: UK Biobank recruited 502,624 participants aged 37-73 years between 2006 and 2010. Baseline exposure data, including 25(OH)D concentration and ethnicity, were linked to COVID-19 test results. Univariable and multivariable logistic regression analyses were performed for the association between 25(OH)D and confirmed COVID-19, and the association between ethnicity and both 25(OH)D and COVID-19. RESULTS: Complete data were available for 348,598 UK Biobank participants. Of these, 449 had confirmed COVID-19 infection. Vitamin D was associated with COVID-19 infection univariably (OR = 0.99; 95% CI 0.99-0.999; p = 0.013), but not after adjustment for confounders (OR = 1.00; 95% CI = 0.998-1.01; p = 0.208). Ethnicity was associated with COVID-19 infection univariably (blacks versus whites OR = 5.32, 95% CI = 3.68-7.70, p-value<0.001; South Asians versus whites OR = 2.65, 95% CI = 1.65-4.25, p-value<0.001). Adjustment for 25(OH)D concentration made little difference to the magnitude of the association. CONCLUSIONS: Our findings do not support a potential link between vitamin D concentrations and risk of COVID-19 infection, nor that vitamin D concentration may explain ethnic differences in COVID-19 infection. Twit Text FOAVip Vitamin D concentrations and COVID-19 infection in UK Biobank ????Diabetes Metab Syndr http://www.kidney.de/pget.php?&tw=1&pmid=32413819 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32413819 #FOAvip English Wikipedia <ref>{{Cite pmid|32413819}}</ref> Vitamin D concentrations and COVID-19 infection in UK Biobank #MMPMID32413819 Hastie CE; Mackay DF; Ho F; Celis-Morales CA; Katikireddi SV; Niedzwiedz CL; Jani BD; Welsh P; Mair FS; Gray SR; O'Donnell CA; Gill JM; Sattar N; Pell JP Diabetes Metab Syndr 2020[Jul]; 14 (4): 561-565 PMID32413819show ga BACKGROUND AND AIMS: COVID-19 and low levels of vitamin D appear to disproportionately affect black and minority ethnic individuals. We aimed to establish whether blood 25-hydroxyvitamin D (25(OH)D) concentration was associated with COVID-19 risk, and whether it explained the higher incidence of COVID-19 in black and South Asian people. METHODS: UK Biobank recruited 502,624 participants aged 37-73 years between 2006 and 2010. Baseline exposure data, including 25(OH)D concentration and ethnicity, were linked to COVID-19 test results. Univariable and multivariable logistic regression analyses were performed for the association between 25(OH)D and confirmed COVID-19, and the association between ethnicity and both 25(OH)D and COVID-19. RESULTS: Complete data were available for 348,598 UK Biobank participants. Of these, 449 had confirmed COVID-19 infection. Vitamin D was associated with COVID-19 infection univariably (OR = 0.99; 95% CI 0.99-0.999; p = 0.013), but not after adjustment for confounders (OR = 1.00; 95% CI = 0.998-1.01; p = 0.208). Ethnicity was associated with COVID-19 infection univariably (blacks versus whites OR = 5.32, 95% CI = 3.68-7.70, p-value<0.001; South Asians versus whites OR = 2.65, 95% CI = 1.65-4.25, p-value<0.001). Adjustment for 25(OH)D concentration made little difference to the magnitude of the association. CONCLUSIONS: Our findings do not support a potential link between vitamin D concentrations and risk of COVID-19 infection, nor that vitamin D concentration may explain ethnic differences in COVID-19 infection. |*Databases, Factual[MESH] |Adult[MESH] |Aged[MESH] |Asian People/*statistics & numerical data[MESH] |Betacoronavirus/pathogenicity[MESH] |Black People/*statistics & numerical data[MESH] |COVID-19[MESH] |Causality[MESH] |Coronavirus Infections/*blood/epidemiology/*ethnology[MESH] |Female[MESH] |Health Surveys[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Pneumonia, Viral/*blood/epidemiology/*ethnology[MESH] |SARS-CoV-2[MESH] |United Kingdom/epidemiology[MESH] |Vitamin D Deficiency/*blood/epidemiology/*ethnology[MESH]Vitamin D concentrations and COVID-19 infection in UK Biobank (epmc).pdf DeepDyve Pubget Overpricing