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10.1016/j.ando.2020.05.001

http://scihub22266oqcxt.onion/10.1016/j.ando.2020.05.001
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32413342!7217100!32413342
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suck abstract from ncbi


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pmid32413342      Ann+Endocrinol+(Paris) 2020 ; 81 (2-3): 101-109
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  • COVID-19 in diabetic patients: Related risks and specifics of management #MMPMID32413342
  • Orioli L; Hermans MP; Thissen JP; Maiter D; Vandeleene B; Yombi JC
  • Ann Endocrinol (Paris) 2020[Jun]; 81 (2-3): 101-109 PMID32413342show ga
  • Diabetes is among the most frequently reported comorbidities in patients infected with COVID-19. According to current data, diabetic patients do not appear to be at increased risk of contracting SARS-CoV-2 compared to the general population. On the other hand, diabetes is a risk factor for developing severe and critical forms of COVID-19, the latter requiring admission to an intensive care unit and/or use of invasive mechanical ventilation, with high mortality rates. The characteristics of diabetic patients at risk for developing severe and critical forms of COVID-19, as well as the prognostic impact of diabetes on the course of COVID-19, are under current investigation. Obesity, the main risk factor for incident type 2 diabetes, is more common in patients with critical forms of COVID-19 requiring invasive mechanical ventilation. On the other hand, COVID-19 is usually associated with poor glycemic control and a higher risk of ketoacidosis in diabetic patients. There are currently no recommendations in favour of discontinuing antihypertensive medications that interact with the renin-angiotensin-aldosterone system. Metformin and SGLT2 inhibitors should be discontinued in patients with severe forms of COVID-19 owing to the risks of lactic acidosis and ketoacidosis. Finally, we advise for systematic screening for (pre)diabetes in patients with proven COVID-19 infection.
  • |Acidosis, Lactic/chemically induced/epidemiology/virology[MESH]
  • |Betacoronavirus/physiology[MESH]
  • |COVID-19[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/*complications/diagnosis/epidemiology/*therapy[MESH]
  • |Critical Illness/epidemiology/therapy[MESH]
  • |Diabetes Mellitus, Type 2/*complications/diagnosis/epidemiology/*therapy[MESH]
  • |Diabetic Ketoacidosis/chemically induced/epidemiology/virology[MESH]
  • |Humans[MESH]
  • |Mass Screening/methods/standards[MESH]
  • |Metformin/therapeutic use[MESH]
  • |Obesity/complications/epidemiology/therapy[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/diagnosis/epidemiology/*therapy[MESH]
  • |Prediabetic State/complications/diagnosis/epidemiology/therapy[MESH]
  • |Renin-Angiotensin System/physiology[MESH]
  • |Risk Factors[MESH]
  • |Risk Management[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]
  • |Sodium-Glucose Transporter 2 Inhibitors/therapeutic use[MESH]


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