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10.1093/eurheartj/ehaa409

http://scihub22266oqcxt.onion/10.1093/eurheartj/ehaa409
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32412631!7239145!32412631
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suck abstract from ncbi


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pmid32412631      Eur+Heart+J 2020 ; 41 (22): 2083-2088
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  • Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era #MMPMID32412631
  • De Rosa S; Spaccarotella C; Basso C; Calabro MP; Curcio A; Filardi PP; Mancone M; Mercuro G; Muscoli S; Nodari S; Pedrinelli R; Sinagra G; Indolfi C
  • Eur Heart J 2020[Jun]; 41 (22): 2083-2088 PMID32412631show ga
  • AIMS: To evaluate the impact of the COVID-19 pandemic on patient admissions to Italian cardiac care units (CCUs). METHODS AND RESULTS: We conducted a multicentre, observational, nationwide survey to collect data on admissions for acute myocardial infarction (AMI) at Italian CCUs throughout a 1 week period during the COVID-19 outbreak, compared with the equivalent week in 2019. We observed a 48.4% reduction in admissions for AMI compared with the equivalent week in 2019 (P < 0.001). The reduction was significant for both ST-segment elevation myocardial infarction [STEMI; 26.5%, 95% confidence interval (CI) 21.7-32.3; P = 0.009] and non-STEMI (NSTEMI; 65.1%, 95% CI 60.3-70.3; P < 0.001). Among STEMIs, the reduction was higher for women (41.2%; P = 0.011) than men (17.8%; P = 0.191). A similar reduction in AMI admissions was registered in North Italy (52.1%), Central Italy (59.3%), and South Italy (52.1%). The STEMI case fatality rate during the pandemic was substantially increased compared with 2019 [risk ratio (RR) = 3.3, 95% CI 1.7-6.6; P < 0.001]. A parallel increase in complications was also registered (RR = 1.8, 95% CI 1.1-2.8; P = 0.009). CONCLUSION: Admissions for AMI were significantly reduced during the COVID-19 pandemic across Italy, with a parallel increase in fatality and complication rates. This constitutes a serious social issue, demanding attention by the scientific and healthcare communities and public regulatory agencies.
  • |*Betacoronavirus[MESH]
  • |*Coronavirus Infections[MESH]
  • |*Myocardial Infarction/complications/diagnosis/mortality/therapy[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19[MESH]
  • |Female[MESH]
  • |Hospitalization/*trends[MESH]
  • |Humans[MESH]
  • |Italy/epidemiology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]


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